SCHEMBL3629448

SCHEMBL3629448

CCCCCCCCON1C(C)(C)CCC(OC(=O)CCC(=O)O)C1(C)C

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NAAA Q02083 2/20 0.39
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
GPR84 Q9NQS5 7/20 0.33
PPARG P37231 7/20 0.33
PPARD Q03181 7/20 0.33
PPARA Q07869 7/20 0.33
HDAC11 Q96DB2 5/20 0.33
TSHR P16473 4/20 0.33
PTPN1 P18031 3/20 0.33
ALDH1A1 P00352 2/20 0.33
TLR2 O60603 2/20 0.33
TDP1 Q9NUW8 2/20 0.33
FABP4 P15090 2/20 0.33
SLC22A6 Q4U2R8 1/20 0.33
SLC22A8 Q8TCC7 1/20 0.33
ESR1 P03372 1/20 0.33
ALOX15 P16050 1/20 0.33
PDE4A P27815 1/20 0.33
PDE3A Q14432 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL194331 0.95 NAAA (0.42) NAAAMEN1KMT2A
SCHEMBL3632141 0.94 NAAA (0.43) NAAAMEN1KMT2AGPR84PPARG
SCHEMBL194536 0.92 NAAA (0.47) NAAA
SCHEMBL28542236 0.92 NAAA (0.47) NAAA
SCHEMBL3668155 0.89 NAAA (0.36) NAAAMEN1KMT2AGPR84PPARG
SCHEMBL9374247 0.84 DGKA (0.43) NAAA
SCHEMBL14973487 0.83 NAAA (0.36) NAAA
SCHEMBL6274158 0.82 PPARG (0.35) NAAAMEN1KMT2AGPR84PPARG
SCHEMBL8915930 0.79 NAAA (0.30) NAAA
SCHEMBL16148704 0.79 PRKCA (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 102 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104755470-A Stabilizer compositions containing substituted chroman compounds and methods of use thereof CYTEC TECH CORP 2015-07-01 CN claimed
CN-102417611-B Stabilizer compositions CYTEC TECH CORP 2014-07-02 CN claimed
CN-103502325-A Processing additives and uses of same in rotational molding CYTEC TECH CORP 2014-01-08 CN claimed
CN-102417611-A Stabilizer compositions CYTEC TECH CORP 2012-04-18 CN claimed
CN-101448888-B stabilizer composition CYTEC TECH CORP 2011-10-05 CN claimed
CN-101448888-A stabilizer composition CYTEC TECH CORP (US) 2009-06-03 CN claimed
CN-101203567-A Scratch resistant polyolefins CIBA SC HOLDING AG (CH) 2008-06-18 CN claimed
CN-1311020-C UV stabilizing additive composition CYTEC TECH CORP (US) 2007-04-18 CN claimed
CN-1875061-A Uv stabilizing additive composition CYTEC TECH CORP (US) 2006-12-06 CN claimed
CN-1247551-C Non-yellowing ortho-dialkylaryl substituted triazine ultraviolet light absorbers CYTEC TECH CORP (US) 2006-03-29 CN claimed
CN-1608103-A UV-stabilized thermoplastic olefins CYTEC TECH CORP (US) 2005-04-20 CN claimed
CN-1478083-A Non-yellowing ortho-dialkylaryl substituted triazine ultraviolet light absorbers CYTEC 2004-02-25 CN claimed
US-11111358-B2 Stabilizer compounds SOLVAY SPECIALTY POLYMERS USA, LLC (US) 2021-09-07 US disclosed
US-11111215-B2 Piperidine-based stabilizers and polymers end-capped with the same SOLVAY SPECIALTY POLYMERS USA, LLC (US) 2021-09-07 US disclosed
US-10954359-B2 Hydroxybenzophenone-based stabilizers and polymers end-capped with the same SOLVAY SPECIALTY POLYMERS USA, LLC (US) 2021-03-23 US disclosed
CN-106458895-B Piperidine-based stabilizers and polymers capped therewith 索尔维特殊聚合物美国有限责任公司 2020-12-11 CN disclosed
CN-1447844-A Process for producing coatings using surface-active photoinitiators CIBA SC HOLDING AG (CH) 2003-10-08 CN disclosed
CN-1444624-A Synergistic stabilizer compositions for color stable pigmented thermoplastic polymers in prolonged contact with water CLARIANT FINANCE BVI LTD (VG) 2003-09-24 CN disclosed
CN-1325401-A Oxime derivatives and their use as latent acids CIBA SC HOLDING AG (CH) 2001-12-05 CN disclosed
CN-1280576-A Morpholino end-capped, hindered amine substituted aminotriazine and their use as light stabilizers CYTEC TECH CORP (US) 2001-01-17 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10954359-B2 Hydroxybenzophenone-based stabilizers and polymers end-capped with the same TYR, HSPA1B, HSPH1 NAAA 3680/4885MEN1 4457/4885KMT2A 3720/4885
US-11111358-B2 Stabilizer compounds HSF1, HEATR1, TBCA NAAA 3164/4885MEN1 4038/4885KMT2A 2210/4885
US-11111215-B2 Piperidine-based stabilizers and polymers end-capped with the same CAPZA1, UNG, CAPZA2 NAAA 2166/4885MEN1 4356/4885KMT2A 3336/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.