SCHEMBL937472

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL937919	0.86	ALDH1A1 (0.38)	RAF1KDRBRAF
	SCHEMBL937005	0.85	RAF1 (0.60)	RAF1KDRBRAFRETPDGFRB
	SCHEMBL938112	0.85	RAF1 (0.41)	RAF1FLT3NPC1RAB9ASMN1; SMN2
	SCHEMBL939118	0.76	RAF1 (0.49)	RAF1KDRFLT3CSF1RNPC1
	SCHEMBL938752	0.76	KDR (0.51)	RAF1KDRFLT3CSF1RBRAF
	SCHEMBL939889	0.73	RAF1 (0.61)	RAF1KDRFLT3CSF1RBRAF
	SCHEMBL3475376	0.71	RAF1 (0.64)	RAF1KDRFLT3CSF1RRET
	SCHEMBL937818	0.71	KDR (0.45)	RAF1KDRBRAFRETPDGFRB
	SCHEMBL939124	0.71	RAF1 (0.43)	RAF1KDRRET
	SCHEMBL937135	0.69	RAF1 (0.37)	RAF1BRAF

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.