Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 10/20 | 0.62 |
| ▸ | NPC1 | O15118 | 7/20 | 0.61 |
| ▸ | RAB9A | P51151 | 7/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.61 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.49 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.49 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6067835 | 0.86 | ABL1 (0.71) | ABL1NPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL9375356 | 0.82 | RAB9A (0.47) | NPC1RAB9ASMN1; SMN2MAPTOPRK1 | |
| SCHEMBL6068323 | 0.81 | ABL1 (0.71) | ABL1NPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL6067860 | 0.80 | ABL1 (0.65) | ABL1NPC1RAB9ASMN1; SMN2PIK3CA | |
| SCHEMBL544194 | 0.78 | DYRK1A (0.62) | ABL1NPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL14189671 | 0.78 | ABL1 (0.70) | ABL1NPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL6068165 | 0.78 | ABL1 (0.63) | ABL1NPC1RAB9ASMN1; SMN2PIK3CA | |
| SCHEMBL1842324 | 0.77 | NPC1 (1.00) | ABL1NPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL6068241 | 0.76 | ABL1 (0.64) | ABL1NPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL6068149 | 0.76 | ABL1 (0.60) | ABL1NPC1RAB9ASMN1; SMN2PIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0356234-B1 | New Benzazole compounds, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO (JP) | 1994-05-11 | — | — | EP | disclosed |
| US-5047411-A | Antiulcer Agents, H2-Receptor Antagonists | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-09-10 | — | — | US | disclosed |
| EP-0356234-A2 | New Benzazole compounds, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1990-02-28 | — | — | EP | disclosed |