Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.47 |
| ▸ | MAPT | P10636 | 6/20 | 0.47 |
| ▸ | NPC1 | O15118 | 5/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 3/20 | 0.47 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.45 |
| ▸ | LDHA | P00338 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | NOS3 | P29474 | 1/20 | 0.41 |
| ▸ | NOS1 | P29475 | 1/20 | 0.41 |
| ▸ | NOS2 | P35228 | 1/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.40 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9382411 | 0.90 | MAPT (0.46) | RAB9AMAPTNPC1OPRK1HTT | |
| SCHEMBL9375013 | 0.82 | ABL1 (0.62) | RAB9AMAPTNPC1OPRK1HTT | |
| SCHEMBL9375983 | 0.81 | RAB9A (0.62) | RAB9AMAPTNPC1HTTS1PR1 | |
| SCHEMBL9381221 | 0.78 | NOS3 (0.47) | RAB9AMAPTNPC1OPRK1HTT | |
| SCHEMBL13766289 | 0.77 | SMN1; SMN2 (0.61) | RAB9AMAPTNPC1HTTLDHA | |
| SCHEMBL9379688 | 0.76 | RAB9A (0.56) | RAB9AMAPTNPC1LDHASMN1; SMN2 | |
| SCHEMBL23965796 | 0.75 | NPC1 (0.58) | RAB9AMAPTNPC1OPRK1HTT | |
| SCHEMBL9377356 | 0.75 | RAB9A (0.41) | RAB9AMAPTNPC1OPRK1HTT | |
| SCHEMBL28204620 | 0.73 | L3MBTL1 (0.50) | S1PR1L3MBTL1CYP1A2CYP2D6 | |
| SCHEMBL9381341 | 0.73 | RAB9A (0.55) | RAB9AMAPTNPC1LDHASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2104578-A | — | — | None | — | — | JP | disclosed |
| EP-0356234-B1 | New Benzazole compounds, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO (JP) | 1994-05-11 | — | — | EP | disclosed |
| US-5047411-A | Antiulcer Agents, H2-Receptor Antagonists | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-09-10 | — | — | US | disclosed |
| JP-H02104578-A | BENZAZOLE DERIVATIVE, PRODUCTION THEREOF AND MEDICINE COMPOSITION CONTAINING THE SAME | FUJISAWA PHARMACEUT CO LTD | 1990-04-17 | — | — | JP | disclosed |
| EP-0356234-A2 | New Benzazole compounds, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1990-02-28 | — | — | EP | disclosed |