Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | CASP3 | P42574 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.46 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.46 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.46 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11739000 | 0.83 | TDP1 (0.57) | KDM4ETDP1L3MBTL1CYP1A1CYP1B1 | |
| Methane SCHEMBL6568809 | 0.82 | TDP1 (0.56) | KDM4ETDP1L3MBTL1CYP1A1CYP1B1 | |
| SCHEMBL9749487 | 0.80 | PTGER1 (0.53) | CYP1A2CYP2D6CYP2C19MEN1KMT2A | |
| SCHEMBL9749454 | 0.79 | SLC2A1 (0.44) | MTNR1ASMN1; SMN2KDM4EMAPTCYP1A1 | |
| SCHEMBL27926016 | 0.78 | CYP1A2 (0.60) | CYP1A2CYP2D6CYP2C19MEN1KMT2A | |
| SCHEMBL7735752 | 0.78 | KMT2A (0.54) | CYP1A2CYP2D6CYP2C19MEN1KMT2A | |
| SCHEMBL9170451 | 0.78 | SLC2A1 (0.45) | SMN1; SMN2KDM4EMAPTATMCYP1A1 | |
| SCHEMBL2314388 | 0.78 | MEN1 (0.66) | CYP1A2CYP2D6CYP2C19MEN1KMT2A | |
| SCHEMBL30490817 | 0.77 | KDM4E (0.46) | SMN1; SMN2KDM4EMAPTATMCYP1A1 | |
| SCHEMBL14064624 | 0.77 | KDM4E (0.46) | SMN1; SMN2KDM4EMAPTATMCYP1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0425946-B1 | Iso- and heterocyclic phenylsulphonamides | BAYER AG (DE) | 1994-08-17 | — | — | EP | disclosed |
| US-5264458-A | Antithrombotic iso- and heterocyclic phenylsulphonamides | BAYER AKTIENGESELLSCHAFT (DE) | 1993-11-23 | — | — | US | disclosed |
| US-5191092-A | ANTITHROMBOTIC ISO- AND HETEROCYCLIC PHENYLSULPHONAMIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1993-03-02 | — | — | US | disclosed |
| EP-0425946-A2 | Iso- and heterocyclic phenylsulphonamides | BAYER AG (DE) | 1991-05-08 | — | — | EP | disclosed |