Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.66 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.55 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.55 |
| ▸ | EGFR | P00533 | 1/20 | 0.52 |
| ▸ | SRC | P12931 | 1/20 | 0.52 |
| ▸ | ACP1 | P24666 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.49 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.47 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 5/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10785269 | 0.83 | GAA (0.70) | GAAAKR1C3AKR1C2EGFRSRC | |
| SCHEMBL9372000 | 0.81 | FABP3 (0.55) | GAAAKR1C3AKR1C2ALDH1A1MAPT | |
| SCHEMBL28349116 | 0.81 | MAPT (0.58) | GAAAKR1C3AKR1C2EGFRSRC | |
| SCHEMBL502786 | 0.79 | GAA (1.00) | GAAAKR1C3AKR1C2EGFRSRC | |
| SCHEMBL28800865 | 0.79 | GAA (0.70) | GAAAKR1C3AKR1C2EGFRSRC | |
| SCHEMBL7004391 | 0.78 | GAA (0.68) | GAAAKR1C3AKR1C2EGFRSRC | |
| SCHEMBL7719696 | 0.78 | GAA (0.68) | GAAAKR1C3AKR1C2EGFRSRC | |
| SCHEMBL10655147 | 0.78 | GAA (0.82) | GAAAKR1C3AKR1C2EGFRSRC | |
| SCHEMBL2211730 | 0.78 | RAB9A (0.60) | GAAEGFRSRCACP1ALDH1A1 | |
| SCHEMBL16438566 | 0.78 | ALDH1A1 (0.53) | GAAALDH1A1MAPTCYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0156250-B1 | Fluoran compounds | HODOGAYA CHEMICAL CO LTD (JP) | 1994-07-27 | — | — | EP | disclosed |
| US-4612558-A | XANTHENE, LEUCO DYES | HODOGAYA CHEMICAL CO., LTD. (JP) | 1986-09-16 | — | — | US | disclosed |
| EP-0156250-A2 | Fluoran compounds | HODOGAYA CHEMICAL CO., LTD. (JP) | 1985-10-02 | — | — | EP | disclosed |