Glycerin

Glycerin

SCHEMBL9375394

C=C(O)COCC(=C)O.OCC(O)CO

nearest known ligand 0.47

Full drug profile on Sugi Atlas →

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.47
ALDH1A1 P00352 1/20 0.47
THRB P10828 1/20 0.33
USP2 O75604 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8608690 0.85 USP2 (0.41) LMNAALDH1A1THRBUSP2
SCHEMBL1682464 0.80
Ethylene Glycol SCHEMBL9377213 0.77 TSHR (0.33)
Glycerin SCHEMBL3290201 0.77 LMNA (0.45) LMNAALDH1A1THRBUSP2
Glycerin SCHEMBL11189173 0.74 LMNA (0.47) LMNAALDH1A1THRBUSP2
Glycerin SCHEMBL27458175 0.72 LMNA (0.90) LMNAALDH1A1THRBUSP2
Glycerin SCHEMBL1900208 0.72 LMNA (0.90) LMNAALDH1A1THRBUSP2
Glycerin SCHEMBL3458178 0.72
Glycerin SCHEMBL1830175 0.70
Glycerin SCHEMBL2305273 0.69 LMNA (0.82) LMNAALDH1A1THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0380409-B1 Process for the preparation of non-ionic surface-active agents from isopropylidene-1,2 epoxypropyl-3 glycerol and from hydroxylated compounds, non-ionic surface-active agents and use of same OREAL (FR) 1994-06-01 EP claimed
EP-0283165-B1 SKIN CONDITIONING COMPOSITION AND METHOD THE PROCTER & GAMBLE COMPANY (US) 1992-10-28 EP disclosed
US-4976953-A WITH NONGREASY, NONTACKY FEEL THE PROCTER & GAMBLE COMPANY (US) 1990-12-11 US disclosed
EP-0283165-A2 Skin conditioning composition and method THE PROCTER & GAMBLE COMPANY (US) 1988-09-21 EP disclosed