Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.90 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.90 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.35 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.30 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.30 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Glycerin SCHEMBL27458175 | 1.00 | LMNA (0.90) | LMNAALDH1A1THRBTDP1OR51E2 | |
| Glycerin SCHEMBL3458178 | 1.00 | — | — | |
| Glycerin SCHEMBL28694326 | 0.95 | — | — | |
| Glycerin SCHEMBL20770227 | 0.95 | — | — | |
| Glycerin SCHEMBL10453101 | 0.95 | LMNA (1.00) | LMNAALDH1A1THRBTDP1OR51E2 | |
| Glycerin SCHEMBL797 | 0.95 | — | — | |
| Glycerin SCHEMBL9439059 | 0.95 | LMNA (1.00) | LMNAALDH1A1THRBTDP1OR51E2 | |
| Glycerin SCHEMBL14278797 | 0.95 | — | — | |
| Glycerin SCHEMBL14278795 | 0.95 | — | — | |
| Glycerin SCHEMBL5610362 | 0.95 | LMNA (1.00) | LMNAALDH1A1THRBTDP1OR51E2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 93 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230226219-A1 | PEG LIPIDOID COMPOUNDS | TRANSLATE BIO, INC. | 2023-07-20 | — | — | US | disclosed |
| EP-4149556-A1 | PEG LIPIDOID COMPOUNDS | Translate Bio, Inc. (US) | 2023-03-22 | — | — | EP | disclosed |
| US-20220016029-A1 | MULTI-PEG LIPID COMPOUNDS | TRANSLATE BIO, INC. | 2022-01-20 | — | — | US | disclosed |
| EP-3583266-B1 | APPARATUS AND METHOD FOR PREPARING ASPHALT AND AGGREGATE MIXTURE | COE WILLIAM B (US) | 2021-12-08 | — | — | EP | disclosed |
| US-11186959-B2 | Apparatus and method for preparing asphalt and aggregate mixture | COE WILLIAM B (US) | 2021-11-30 | — | — | US | disclosed |
| WO-2021231697-A1 | PEG LIPIDOID COMPOUNDS | TRANSLATE BIO, INC. (US) | 2021-11-18 | — | — | WO | disclosed |
| EP-3877444-A1 | MULTI-PEG LIPID COMPOUNDS | Translate Bio, Inc. (US) | 2021-09-15 | — | — | EP | disclosed |
| EP-3876994-A2 | PEG LIPIDOID COMPOUNDS | Translate Bio, Inc. (US) | 2021-09-15 | — | — | EP | disclosed |
| US-11078633-B2 | Pavement repair system | COE WILIAM B (US) | 2021-08-03 | — | — | US | disclosed |
| US-10934669-B2 | Method for preparing asphalt paving material utilizing solid phase autoregenerative cohesion | COE WILLIAM B (US) | 2021-03-02 | — | — | US | disclosed |
| WO-2009155115-A2 | COATINGS AND SURFACE TREATMENTS HAVING ACTIVE ENZYMES AND PEPTIDES | REACTIVE SURFACES, LTD. (US) | 2009-12-23 | — | — | WO | disclosed |
| US-20090238811-A1 | Enzymatic Antimicrobial and Antifouling Coatings and Polymeric Materials | REACTIVE SURFACES LTD. | 2009-09-24 | — | — | US | disclosed |
| WO-2008024753-A2 | LIPID-DERIVED NANOPARTICLES FOR BRAIN-TARGETED DRUG DELIVERY | WAYNE STATE UNIVERSITY (US) | 2008-02-28 | — | — | WO | disclosed |
| EP-1660596-A1 | MICROORGANISM COATING COMPONENTS, COATINGS, AND COATED SURFACES | McDaniel, Steven C. (US) | 2006-05-31 | — | — | EP | disclosed |
| WO-2005026269-A1 | MICROORGANISM COATING COMPONENTS, COATINGS, AND COATED SURFACES | MCDANIEL C STEVEN (US) | 2005-03-24 | — | — | WO | disclosed |
| US-20040175407-A1 | Microorganism coating components, coatings, and coated surfaces | REACTIVE SURFACES, LTD. | 2004-09-09 | — | — | US | disclosed |
| EP-0648239-A4 | BIOCOMPATIBLE POLYMER CONJUGATES. | COLLAGEN CORP (US) | 1995-09-27 | — | — | EP | disclosed |
| EP-0648239-A1 | BIOCOMPATIBLE POLYMER CONJUGATES | COLLAGEN CORPORATION (US) | 1995-04-19 | — | — | EP | disclosed |
| US-5324775-A | Bound to a synthetic non-immunogenic hydrophilic polyethylene glycol polymer; can be injected into humans to augment soft tissue | COLLAGEN CORPORATION (US) | 1994-06-28 | — | — | US | disclosed |
| WO-1994001483-A1 | BIOCOMPATIBLE POLYMER CONJUGATES | COLLAGEN CORPORATION (US) | 1994-01-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220016029-A1 | MULTI-PEG LIPID COMPOUNDS | LIPG, HDLBP, LIPC | LMNA 1955/4885ALDH1A1 4097/4885THRB 2625/4885 |
| US-20230226219-A1 | PEG LIPIDOID COMPOUNDS | LIPG, ABCB4, HDLBP | LMNA 1547/4885ALDH1A1 3688/4885THRB 1980/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.