Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9434404 | 0.85 | ALOX5 (0.58) | ALOX5 | |
| SCHEMBL9369871 | 0.85 | ALOX5 (0.60) | ALOX5 | |
| SCHEMBL9433848 | 0.83 | ALOX5 (0.50) | ALOX5 | |
| SCHEMBL9369033 | 0.75 | ALOX5 (0.76) | ALOX5 | |
| SCHEMBL9597801 | 0.74 | ALOX5 (0.71) | ALOX5 | |
| SCHEMBL9370145 | 0.74 | ALOX5 (0.75) | ALOX5 | |
| SCHEMBL9373150 | 0.73 | ALOX5 (0.52) | ALOX5 | |
| SCHEMBL9368571 | 0.73 | ALOX5 (0.48) | ALOX5 | |
| SCHEMBL9375597 | 0.73 | ALOX5 (0.82) | ALOX5 | |
| SCHEMBL9434226 | 0.73 | ALOX5 (0.55) | ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0351194-B1 | Thiazole derivatives having a 5-lipoxygenase-inhibiting activity | ICI PLC (GB) | 1994-06-15 | — | — | EP | disclosed |
| US-5196422-A | Antiinflammatory agents, antiallergens | ICI PHARMA (FR) | 1993-03-23 | — | — | US | disclosed |
| US-5089513-A | Antiinflammatory agents; antiallergens; asthma; side effect reduction | ICI PHARMA (FR) | 1992-02-18 | — | — | US | disclosed |
| EP-0351194-A2 | Thiazole derivatives having a 5-lipoxygenase-inhibiting activity | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-01-17 | — | — | EP | disclosed |