Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 15/20 | 0.58 |
| ▸ | GRM5 | P41594 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9375547 | 0.85 | ALOX5 (0.56) | ALOX5 | |
| SCHEMBL9433194 | 0.85 | ALOX5 (0.79) | ALOX5GRM5 | |
| SCHEMBL9369871 | 0.83 | ALOX5 (0.60) | ALOX5 | |
| SCHEMBL9433848 | 0.82 | ALOX5 (0.50) | ALOX5L3MBTL1 | |
| SCHEMBL9434038 | 0.81 | ALOX5 (0.62) | ALOX5GRM5 | |
| SCHEMBL9433999 | 0.81 | ALOX5 (0.62) | ALOX5GRM5 | |
| SCHEMBL9597801 | 0.76 | ALOX5 (0.71) | ALOX5 | |
| SCHEMBL9373150 | 0.74 | ALOX5 (0.52) | ALOX5 | |
| SCHEMBL9368571 | 0.74 | ALOX5 (0.48) | ALOX5RAB9A | |
| SCHEMBL9434226 | 0.74 | ALOX5 (0.55) | ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5283245-A | Antiinflammatory agent, antiallergens | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1994-02-01 | — | — | US | disclosed |
| EP-0381375-B1 | HETEROCYCLIC DERIVATIVES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-11-11 | — | — | EP | disclosed |
| US-5089495-A | Lipoxygenase inhibitors | IMPERIAL CHEMICAL INDUSTRIES PLC (FR) | 1992-02-18 | — | — | US | disclosed |