Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 1/20 | 0.42 |
| ▸ | NOS1 | P29475 | 1/20 | 0.42 |
| ▸ | NOS2 | P35228 | 1/20 | 0.42 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.35 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.34 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.34 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.34 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9376768 | 0.82 | GFER (0.48) | NOS3NOS1NOS2KDM4ESSTR4 | |
| SCHEMBL9379313 | 0.81 | TSHR (0.46) | KDM4EPARP1SMN1; SMN2CYP3A4ALOX15 | |
| SCHEMBL26971380 | 0.76 | KDM4E (0.61) | NOS3NOS1NOS2KDM4ESSTR4 | |
| SCHEMBL9382376 | 0.76 | RAB9A (0.55) | TP53SMN1; SMN2CYP3A4NPC1HPGD | |
| Hydrochloric Acid SCHEMBL9379279 | 0.74 | FABP6 (0.42) | NOS3NOS1NOS2KDM4EPRMT5 | |
| SCHEMBL2777255 | 0.73 | TDP1 (0.48) | SKP2KDM4ECYP17A1CYP19A1CYP11B1 | |
| SCHEMBL9376123 | 0.72 | HRH1 (0.52) | KDM4ECYP3A4ALOX15TDP1LMNA | |
| SCHEMBL30839509 | 0.72 | NOS3 (0.48) | NOS3NOS1NOS2SSTR4TDP1 | |
| SCHEMBL701433 | 0.72 | NOS3 (0.48) | NOS3NOS1NOS2SSTR4TDP1 | |
| SCHEMBL17849499 | 0.70 | SSTR4 (0.47) | NOS3NOS1NOS2KDM4ESSTR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0356234-B1 | New Benzazole compounds, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO (JP) | 1994-05-11 | — | — | EP | disclosed |
| US-5047411-A | Antiulcer Agents, H2-Receptor Antagonists | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-09-10 | — | — | US | disclosed |
| EP-0356234-A2 | New Benzazole compounds, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1990-02-28 | — | — | EP | disclosed |