Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 5/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.41 |
| ▸ | DRD2 | P14416 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | APP | P05067 | 2/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.38 |
| ▸ | PI4KA | P42356 | 3/20 | 0.38 |
| ▸ | PIK3CG | P48736 | 3/20 | 0.38 |
| ▸ | PI4KB | Q9UBF8 | 3/20 | 0.38 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.38 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9375280 | 0.87 | RAB9A (0.49) | CYP3A4CYP1A2CYP2C19RAB9ANPC1 | |
| Hydrochloric Acid SCHEMBL9383081 | 0.84 | RAB9A (0.46) | CYP3A4CYP1A2CYP2C19RAB9ANPC1 | |
| SCHEMBL9379336 | 0.82 | NPC1 (0.57) | CYP3A4CYP1A2CYP2C19RAB9ANPC1 | |
| SCHEMBL9378131 | 0.82 | CREBBP (0.38) | RAB9AALDH1A1 | |
| SCHEMBL9376391 | 0.81 | CYP19A1 (0.48) | RAB9ANPC1ALDH1A1TP53 | |
| SCHEMBL9379863 | 0.80 | CREBBP (0.36) | RAB9ANPC1SMN1; SMN2MAPTPIK3CG | |
| SCHEMBL9375832 | 0.79 | KDM4E (0.39) | CYP3A4CYP1A2RAB9AMAPTTSHR | |
| Hydrochloric Acid SCHEMBL9377697 | 0.79 | CREBBP (0.36) | RAB9AMAPTALDH1A1PIK3CG | |
| SCHEMBL9376418 | 0.78 | RAB9A (0.48) | CYP3A4CYP1A2CYP2C19RAB9ANPC1 | |
| SCHEMBL9376180 | 0.78 | TYMS (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0356234-B1 | New Benzazole compounds, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO (JP) | 1994-05-11 | — | — | EP | disclosed |
| US-5047411-A | Antiulcer Agents, H2-Receptor Antagonists | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-09-10 | — | — | US | disclosed |
| EP-0356234-A2 | New Benzazole compounds, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1990-02-28 | — | — | EP | disclosed |