Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.39 |
| ▸ | CREBBP | Q92793 | 8/20 | 0.36 |
| ▸ | BRD4 | O60885 | 6/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | IGF1R | P08069 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | EP300 | Q09472 | 1/20 | 0.35 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9378131 | 0.90 | CREBBP (0.38) | KDM4ERAB9AALDH1A1HPGDCREBBP | |
| SCHEMBL9380048 | 0.89 | CREBBP (0.36) | KDM4ERAB9AALDH1A1HPGDCREBBP | |
| SCHEMBL9377374 | 0.86 | USP7 (0.41) | KDM4ERAB9AALDH1A1HPGDMAPT | |
| SCHEMBL9374989 | 0.86 | KDM4E (0.39) | KDM4ERAB9AALDH1A1CREBBPBRD4 | |
| SCHEMBL9376391 | 0.85 | CYP19A1 (0.48) | KDM4ERAB9AALDH1A1HPGDCREBBP | |
| SCHEMBL9375664 | 0.84 | KDM4E (0.37) | KDM4ERAB9AALDH1A1MAPTMEN1 | |
| SCHEMBL9376273 | 0.84 | KDM4E (0.37) | KDM4ERAB9AALDH1A1MAPTMEN1 | |
| SCHEMBL9376914 | 0.83 | PLAU (0.38) | KDM4ERAB9AALDH1A1HPGDMAPT | |
| SCHEMBL9376169 | 0.81 | ALDH1A1 (0.42) | KDM4ERAB9AALDH1A1HPGDMAPT | |
| SCHEMBL9376989 | 0.81 | KMT2A (0.35) | KDM4ERAB9AMAPTMEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0356234-B1 | New Benzazole compounds, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO (JP) | 1994-05-11 | — | — | EP | disclosed |
| US-5047411-A | Antiulcer Agents, H2-Receptor Antagonists | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-09-10 | — | — | US | disclosed |
| EP-0356234-A2 | New Benzazole compounds, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1990-02-28 | — | — | EP | disclosed |