Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | GRM5 | P41594 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.36 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 4/20 | 0.35 |
| ▸ | RAB9A | P51151 | 4/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.35 |
| ▸ | PKM | P14618 | 2/20 | 0.35 |
| ▸ | MITF | O75030 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | METAP2 | P50579 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10539492 | 0.85 | KMT2A (0.44) | KMT2ALMNAGPBAR1GRM5TGFBR1 | |
| SCHEMBL3425870 | 0.84 | KMT2A (0.70) | KMT2ALMNAGPBAR1MAPK1NPC1 | |
| SCHEMBL8951976 | 0.81 | LMNA (0.70) | KMT2ALMNAGRM5MAPK1NPC1 | |
| SCHEMBL9217242 | 0.80 | LMNA (0.58) | KMT2ALMNAGRM5MAPK1FFAR1 | |
| SCHEMBL2015105 | 0.80 | LMNA (0.58) | KMT2ALMNAGRM5MAPK1TGFBR1 | |
| SCHEMBL9370776 | 0.79 | MAPT (0.41) | KMT2ALMNAPTPN1MAPK1FFAR1 | |
| SCHEMBL3630556 | 0.78 | IDO1 (0.50) | KMT2ALMNAPTPN1NPC1RAB9A | |
| SCHEMBL10550629 | 0.77 | PTPN1 (0.43) | KMT2ALMNAPTPN1NPC1RAB9A | |
| SCHEMBL6351866 | 0.76 | IDO1 (0.48) | KMT2ALMNAPTPN1MAPK1NPC1 | |
| SCHEMBL9369412 | 0.76 | LMNA (0.57) | KMT2ALMNAPTPN1GRM5MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0259139-B1 | Pyridinylpyrimidine derivatives, method for production thereof and a plant disease protectant containing them as the active ingredient | SUMITOMO CHEMICAL CO (JP) | 1994-01-26 | — | — | EP | disclosed |
| US-4783466-A | Novel pyridinylpyrimidine derivatives, method for production thereof and a plant disease protectant containing them as the active ingredient | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1988-11-08 | — | — | US | disclosed |
| EP-0259139-A2 | Pyridinylpyrimidine derivatives, method for production thereof and a plant disease protectant containing them as the active ingredient | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1988-03-09 | — | — | EP | disclosed |