Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.70 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | DPP4 | P27487 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11286099 | 0.90 | KMT2A (0.56) | KMT2ALMNACYP1A2CYP2C19MEN1 | |
| SCHEMBL9375764 | 0.84 | KMT2A (0.55) | KMT2ALMNACYP1A2CYP2C19MEN1 | |
| SCHEMBL31296065 | 0.82 | KMT2A (1.00) | KMT2ALMNAMEN1NPC1TSHR | |
| SCHEMBL24577342 | 0.81 | KDM4E (0.53) | KMT2ALMNACYP1A2CYP2C19MEN1 | |
| SCHEMBL12653948 | 0.78 | KMT2A (0.60) | KMT2ALMNAMEN1TSHRMAPK1 | |
| SCHEMBL786243 | 0.78 | KMT2A (0.60) | KMT2ALMNACYP1A2CYP2C19TSHR | |
| SCHEMBL11810775 | 0.77 | HSP90AA1 (0.55) | KMT2ALMNACYP1A2CYP2C19MEN1 | |
| SCHEMBL1772953 | 0.77 | LMNA (1.00) | KMT2ALMNACYP1A2CYP2C19MEN1 | |
| SCHEMBL12697515 | 0.76 | CYP1A2 (0.49) | KMT2ALMNACYP1A2CYP2C19MEN1 | |
| SCHEMBL6172768 | 0.76 | CYP1A2 (0.49) | KMT2ALMNACYP1A2CYP2C19MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7731985-B2 | 4-aminopyrimidines and their use for the antimicrobial treatment of surfaces | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2010-06-08 | — | — | US | disclosed |
| EP-1484971-B1 | USE OF 4-AMINOPYRIMIDINES FOR THE ANTIMICROBIAL TREATMENT OF SURFACES | CIBA SC HOLDING AG (CH) | 2007-07-04 | — | — | EP | disclosed |
| US-20050143387-A1 | 4-Aminopyrimidines and their use for the antimicrobial treatment of surfaces | CIBA SPECIALTY CHEMICALS CORP. | 2005-06-30 | — | — | US | disclosed |
| EP-1484971-A1 | 4-AMINOPYRIMIDINES AND THEIR USE FOR THE ANTIMICROBIAL TREATMENT OF SURFACES | Ciba SC Holding AG (CH) | 2004-12-15 | — | — | EP | disclosed |
| WO-2003077656-A1 | 4-AMINOPYRIMIDINES AND THEIR USE FOR THE ANTIMICROBIAL TREATMENT OF SURFACES | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2003-09-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050143387-A1 | 4-Aminopyrimidines and their use for the antimicrobial treatment of surfaces | DPM1, UNG, DPYD | KMT2A 3109/4885LMNA 4211/4885CYP1A2 691/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.