Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.45 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.45 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.45 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9375784 | 1.00 | ALDH1A1 (0.54) | ALDH1A1KMT2AMEN1SMN1; SMN2TP53 | |
| SCHEMBL14454666 | 0.89 | ALDH1A1 (0.54) | ALDH1A1KMT2AMEN1SMN1; SMN2TP53 | |
| SCHEMBL6703265 | 0.86 | ALDH1A1 (0.51) | ALDH1A1KMT2AMEN1SMN1; SMN2TP53 | |
| SCHEMBL4432206 | 0.86 | ALDH1A1 (0.51) | ALDH1A1KMT2AMEN1SMN1; SMN2TP53 | |
| SCHEMBL4425700 | 0.86 | ALDH1A1 (0.51) | ALDH1A1KMT2AMEN1SMN1; SMN2TP53 | |
| SCHEMBL5276860 | 0.85 | ALDH1A1 (0.50) | ALDH1A1KMT2AMEN1NPC1RAB9A | |
| SCHEMBL5276866 | 0.85 | ALDH1A1 (0.50) | ALDH1A1KMT2AMEN1NPC1RAB9A | |
| SCHEMBL31425237 | 0.84 | SGMS2 (0.47) | ALDH1A1KMT2AMEN1SMN1; SMN2TP53 | |
| SCHEMBL5582439 | 0.84 | MEN1 (0.54) | ALDH1A1KMT2AMEN1PDK1PDK2 | |
| SCHEMBL5582438 | 0.84 | MEN1 (0.54) | ALDH1A1KMT2AMEN1PDK1PDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0590022-A1 | IMIDAZO 1,5-a]QUINOXALINES | PHARMACIA & UPJOHN COMPANY (US) | 1994-04-06 | — | — | EP | disclosed |