Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2956244 | 0.83 | CA12 (0.45) | FDPSLMNAALDH1A1KCNA5HSD17B10 | |
| SCHEMBL707791 | 0.82 | TSHR (0.47) | FDPSSMN1; SMN2NPC1LMNARAB9A | |
| SCHEMBL27563232 | 0.78 | HRH3 (0.46) | FDPSLMNAALDH1A1KDM4EKCNA5 | |
| SCHEMBL23884931 | 0.77 | FDPS (0.53) | FDPSSMN1; SMN2NPC1LMNARAB9A | |
| SCHEMBL10700245 | 0.77 | FDPS (0.53) | FDPSSMN1; SMN2NPC1LMNARAB9A | |
| SCHEMBL18235430 | 0.76 | ALDH1A1 (0.50) | FDPSSMN1; SMN2NPC1LMNARAB9A | |
| SCHEMBL11528070 | 0.76 | ALDH1A1 (0.57) | FDPSSMN1; SMN2NPC1LMNARAB9A | |
| SCHEMBL16974746 | 0.76 | ALDH1A1 (0.57) | FDPSSMN1; SMN2NPC1LMNARAB9A | |
| SCHEMBL11952596 | 0.76 | FDPS (0.47) | FDPSSMN1; SMN2NPC1LMNARAB9A | |
| SCHEMBL16974747 | 0.75 | ALDH1A1 (0.56) | FDPSSMN1; SMN2NPC1LMNARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0588785-A1 | UREA BASED LIPOXYGENASE INHIBITING COMPOUNDS | ABBOTT LABORATORIES (US) | 1994-03-30 | — | — | EP | disclosed |
| US-5185363-A | Administering for treatment of inflammatory diseases | ABBOTT LABORATORIES (US) | 1993-02-09 | — | — | US | disclosed |
| EP-0588785-A4 | UREA BASED LIPOXYGENASE INHIBITING COMPOUNDS. | ABBOTT LAB (US) | 1991-12-30 | — | — | EP | disclosed |
| WO-1990012008-A1 | UREA BASED LIPOXYGENASE INHIBITING COMPOUNDS | ABBOTT LABORATORIES (US) | 1990-10-18 | — | — | WO | disclosed |