Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.42 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.42 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.41 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.41 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.41 |
| ▸ | NHERF1 | O14745 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.40 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9378204 | 0.92 | KCNK3 (0.51) | MAPK14MAPTTP53NPC1RAB9A | |
| SCHEMBL9378850 | 0.85 | KMT2A (0.50) | MAPK14TP53NPC1RAB9APDK2 | |
| SCHEMBL9379254 | 0.84 | KMT2A (0.54) | MAPK14MAPTTP53NPC1RAB9A | |
| SCHEMBL9376028 | 0.83 | NPC1 (0.49) | MAPK14NPC1RAB9APDK2PDK4 | |
| SCHEMBL9375312 | 0.83 | HDAC1 (0.50) | MAPK14PDK2PDK4 | |
| SCHEMBL9379514 | 0.83 | RAB9A (0.55) | MAPK14MAPTNPC1RAB9AKMT2A | |
| SCHEMBL9379050 | 0.83 | CNR2 (0.48) | MAPK14MAPTTP53NPC1RAB9A | |
| SCHEMBL9380251 | 0.82 | RAB9A (0.58) | MAPK14NPC1RAB9APDK2PDK4 | |
| SCHEMBL9376565 | 0.81 | NPC1 (0.60) | MAPTNPC1RAB9AKMT2AMEN1 | |
| SCHEMBL9374739 | 0.81 | TSHR (0.54) | MAPTTP53NPC1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0344634-B1 | Bicyclic carboxamides, process for their preparation and medicaments containing them | BOEHRINGER MANNHEIM GMBH (DE) | 1994-03-30 | — | — | EP | disclosed |
| US-5019587-A | Anticoagulants | BOEHRINGER MANNHEIM GMBH (DE) | 1991-05-28 | — | — | US | disclosed |