SCHEMBL9376149

SCHEMBL9376149

O=C(Nc1ncc([N+](=O)[O-])cc1Br)c1ccccc1

nearest known ligand 0.55

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.55
KMT2A Q03164 6/20 0.52
NPC1 O15118 3/20 0.52
MEN1 O00255 3/20 0.52
POLB P06746 2/20 0.52
MITF O75030 1/20 0.52
RAB9A P51151 1/20 0.52
KCNH2 Q12809 1/20 0.52
ALOX5 P09917 1/20 0.48
TDP1 Q9NUW8 2/20 0.47
HDAC2 Q92769 1/20 0.47
HCAR3 P49019 1/20 0.47
ABCG2 Q9UNQ0 2/20 0.46
ALDH1A1 P00352 2/20 0.46
SMN1; SMN2 Q16637 2/20 0.46
CACNA1B Q00975 1/20 0.46
APBA1 Q02410 1/20 0.46
SNCA P37840 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15043008 0.81 KMT2A (0.58) MAPTKMT2ANPC1MEN1POLB
SCHEMBL914646 0.79 GAA (0.54) MAPTKMT2AMEN1TDP1ALDH1A1
SCHEMBL15999439 0.78 MEN1 (0.56) MAPTKMT2AMEN1TDP1ABCG2
SCHEMBL2063757 0.77 KMT2A (0.60) MAPTKMT2ANPC1MEN1POLB
SCHEMBL27720607 0.77 KMT2A (0.58) MAPTKMT2ANPC1MEN1POLB
SCHEMBL27699809 0.77 KMT2A (0.54) MAPTKMT2ANPC1MEN1POLB
SCHEMBL27699748 0.77 KMT2A (0.54) MAPTKMT2ANPC1MEN1POLB
SCHEMBL31399753 0.77 KMT2A (0.62) MAPTKMT2ANPC1MEN1POLB
SCHEMBL1842636 0.77 KMT2A (0.62) MAPTKMT2ANPC1MEN1POLB
SCHEMBL24603643 0.75 GAA (0.42) MAPTKMT2ANPC1MEN1KCNH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0333185-B1 Cyan dye-forming coupler and silver halide photosensitive material containing the same FUJI PHOTO FILM CO LTD (JP) 1994-12-28 EP disclosed
US-5260177-A Cyan dye-forming coupler, pivaloylacetoanilide yellow coupler, pyrazoloazole magenta coupler FUJI PHOTO FILM CO., LTD. (JP) 1993-11-09 US disclosed
EP-0333185-A2 Cyan dye-forming coupler and silver halide photosensitive material containing the same FUJI PHOTO FILM CO., LTD. (JP) 1989-09-20 EP disclosed