Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 3/20 | 0.58 |
| ▸ | HTR1A | P08908 | 2/20 | 0.58 |
| ▸ | HTR2A | P28223 | 1/20 | 0.58 |
| ▸ | DRD5 | P21918 | 2/20 | 0.52 |
| ▸ | DRD3 | P35462 | 2/20 | 0.52 |
| ▸ | HTR7 | P34969 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9380479 | 0.99 | DRD2 (0.58) | DRD2HTR1AHTR2ADRD5DRD3 | |
| SCHEMBL9377355 | 0.84 | HTR1A (0.65) | DRD2HTR1AHTR2ADRD3HTR7 | |
| Hydrochloric Acid SCHEMBL9381340 | 0.82 | HTR1A (0.62) | DRD2HTR1AHTR2ADRD3HTR7 | |
| SCHEMBL9601759 | 0.82 | HTR1A (0.70) | DRD2HTR1AHTR2AHTR7 | |
| SCHEMBL30649298 | 0.82 | HTR1A (0.70) | DRD2HTR1AHTR2AHTR7 | |
| Hydrochloric Acid SCHEMBL9382359 | 0.81 | HTR1A (0.69) | DRD2HTR1AHTR2AHTR7 | |
| Hydrochloric Acid SCHEMBL9595406 | 0.80 | HTR1A (0.71) | DRD2HTR1AHTR2AHTR7 | |
| Hydrochloric Acid SCHEMBL9379578 | 0.80 | HTR1A (0.71) | DRD2HTR1AHTR2AHTR7 | |
| Hydrochloric Acid SCHEMBL9376327 | 0.79 | HTR1A (0.66) | DRD2HTR1AHTR2AHTR7 | |
| SCHEMBL9377459 | 0.78 | DRD2 (0.55) | DRD2HTR1AHTR2ADRD3HTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0625978-A1 | PIPERAZINE AND PIPERIDINE DERIVATIVES, AND THEIR USE AS ANTIPSYCHOTICS | THE WELLCOME FOUNDATION LIMITED (GB) | 1994-11-30 | — | — | EP | disclosed |