Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 4/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 2/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | MMP9 | P14780 | 1/20 | 0.34 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9375817 | 0.88 | NPC1 (0.51) | NPC1RAB9AALDH1A1KDM4ECYP1A2 | |
| SCHEMBL9377017 | 0.87 | GAA (0.39) | NPC1RAB9AALDH1A1KDM4ECYP1A2 | |
| SCHEMBL9501982 | 0.83 | GAA (0.41) | NPC1RAB9AALDH1A1KDM4ECYP1A2 | |
| SCHEMBL5697093 | 0.82 | NPC1 (0.53) | NPC1RAB9AALDH1A1KDM4ECYP1A2 | |
| SCHEMBL9408785 | 0.81 | NPC1 (0.52) | NPC1RAB9AALDH1A1KDM4ECYP1A2 | |
| SCHEMBL15910157 | 0.81 | NPC1 (0.55) | NPC1RAB9AALDH1A1KDM4ECYP1A2 | |
| SCHEMBL9408803 | 0.81 | RAB9A (0.47) | NPC1RAB9AALDH1A1KDM4ECYP1A2 | |
| SCHEMBL1532693 | 0.80 | NPC1 (0.49) | NPC1RAB9AALDH1A1KDM4ECYP1A2 | |
| SCHEMBL2146927 | 0.80 | NPC1 (0.53) | NPC1RAB9AALDH1A1KDM4ECYP1A2 | |
| SCHEMBL9408831 | 0.79 | NPC1 (0.44) | NPC1RAB9AALDH1A1KDM4ECYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0308886-B1 | Dianhydride coupled polymer stabilizers | ATOCHEM NORTH AMERICA (US) | 1994-11-23 | — | — | EP | disclosed |
| US-4874803-A | HEAT AND OXIDATION RESISTANCE; PHOTOSTABILITY | PENNWALT CORPORATION (US) | 1989-10-17 | — | — | US | disclosed |
| EP-0308886-A2 | Dianhydride coupled polymer stabilizers | ATOCHEM NORTH AMERICA, INC. (US) | 1989-03-29 | — | — | EP | disclosed |