SCHEMBL9501982

SCHEMBL9501982

Cc1cc(CCC(=O)NN)cc(-n2nc3ccc(Cl)cc3n2)c1O

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.41
ALDH1A1 P00352 3/20 0.40
MAPT P10636 6/20 0.39
TP53 P04637 2/20 0.39
RXFP1 Q9HBX9 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.36
NPC1 O15118 1/20 0.36
RAB9A P51151 1/20 0.36
KDM4E B2RXH2 3/20 0.35
HPGD P15428 2/20 0.35
CYP1A2 P05177 1/20 0.35
CYP2C9 P11712 1/20 0.35
CYP2C19 P33261 1/20 0.35
POLB P06746 1/20 0.35
PKM P14618 1/20 0.35
GFER P55789 1/20 0.35
ALOX15 P16050 1/20 0.34
MAPK1 P28482 1/20 0.34
CNR1 P21554 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9165686 0.88 GAA (0.45) GAAALDH1A1MAPTTP53SMN1; SMN2
SCHEMBL12919747 0.87 FFAR1 (0.41) ALDH1A1MAPTTP53SMN1; SMN2NPC1
SCHEMBL9501153 0.87 GAA (0.58) GAAALDH1A1MAPTTP53RXFP1
SCHEMBL9376191 0.83 NPC1 (0.44) GAAALDH1A1MAPTTP53RXFP1
SCHEMBL13700429 0.82 NPC1 (0.42) ALDH1A1MAPTTP53RXFP1SMN1; SMN2
SCHEMBL9377017 0.79 GAA (0.39) GAAALDH1A1MAPTTP53RXFP1
Diethylamine SCHEMBL7562154 0.79 NPC1 (0.38) ALDH1A1MAPTTP53RXFP1SMN1; SMN2
SCHEMBL9291461 0.78 NPC1 (0.36) ALDH1A1MAPTSMN1; SMN2L3MBTL1NPC1
SCHEMBL12919745 0.78 EPHX2 (0.41) ALDH1A1L3MBTL1CNR1
SCHEMBL8017347 0.77 NPC1 (0.58) GAAALDH1A1MAPTTP53SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0303988-B1 POLYMER BOUND UV STABILIZERS ATOCHEM NORTH AMERICA, INC. (US) 1993-05-12 EP disclosed
US-5206378-A Ultraviolet light stabilizers ELF ATOCHEM NORTH AMERICA, INC. (US) 1993-04-27 US disclosed
EP-0303986-B1 MULTIPURPOSE POLYMER BOUND STABILIZERS ATOCHEM NORTH AMERICA, INC. (US) 1992-07-29 EP disclosed
US-5096974-A Reacting primary amino or hydrazido-substituted stabilizers with maleic anhydride polymers; nonextractable and nonvolatile in polymer blends ATOCHEM NORTH AMERICA, INC. (US) 1992-03-17 US disclosed
US-5096977-A Anhydride polymers ATOCHEM NORTH AMERICA, INC. (US) 1992-03-17 US disclosed
US-4981915-A HYDRAZIDE MODIFIERS ATOCHEM NORTH AMERICA, INC. (US) 1991-01-01 US disclosed
US-4981914-A HYDRAZIDE MODIFIERS ATOCHEM NORTH AMERICA, INC. (US) 1991-01-01 US disclosed
US-4868246-A PRIMARY AMINO OR HYDRAZIDO UV ABSORBERS CHEMICALLY BOUND TO POLYMER ANHYDRIDE GROUPS PENNWALT CORPORATION (US) 1989-09-19 US disclosed
US-4863999-A IMIDES OR AMIC ACIDS OF ANHDRIDE POLYMERS PENNWALT CORPORATION (US) 1989-09-05 US disclosed
EP-0303986-A2 Multipurpose polymer bound stabilizers ATOCHEM NORTH AMERICA, INC. (US) 1989-02-22 EP disclosed