Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 4/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.48 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.48 |
| ▸ | MDM4 | O15151 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | FABP7 | O15540 | 1/20 | 0.44 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3470475 | 1.00 | CASP3 (0.57) | CASP3KMT2AEPHX2PIN1MDM4 | |
| SCHEMBL29401008 | 1.00 | CASP3 (0.57) | CASP3KMT2AEPHX2PIN1MDM4 | |
| SCHEMBL6779154 | 1.00 | CASP3 (0.57) | CASP3KMT2AEPHX2PIN1MDM4 | |
| SCHEMBL28946743 | 0.89 | CASP3 (0.49) | CASP3KMT2AEPHX2PIN1MDM4 | |
| SCHEMBL17094815 | 0.89 | CASP3 (0.49) | CASP3KMT2AEPHX2PIN1MDM4 | |
| SCHEMBL178791 | 0.88 | CASP3 (0.60) | CASP3KMT2AEPHX2PIN1MDM4 | |
| SCHEMBL10173305 | 0.88 | CASP3 (0.58) | CASP3KMT2AEPHX2PIN1MDM4 | |
| SCHEMBL120703 | 0.88 | CASP3 (0.60) | CASP3KMT2AEPHX2PIN1MDM4 | |
| SCHEMBL2591012 | 0.88 | CASP3 (0.58) | CASP3KMT2AEPHX2PIN1MDM4 | |
| SCHEMBL13044090 | 0.88 | CASP3 (0.58) | CASP3KMT2AEPHX2PIN1MDM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0625978-A1 | PIPERAZINE AND PIPERIDINE DERIVATIVES, AND THEIR USE AS ANTIPSYCHOTICS | THE WELLCOME FOUNDATION LIMITED (GB) | 1994-11-30 | — | — | EP | disclosed |
| WO-1993016073-A1 | PIPERAZINE AND PIPERIDINE DERIVATIVES, AND THEIR USE AS ANTIPSYCHOTICS | THE WELLCOME FOUNDATION LIMITED (GB) | 1993-08-19 | — | — | WO | disclosed |