Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | GFER | P55789 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | HTR6 | P50406 | 6/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | FEN1 | P39748 | 2/20 | 0.37 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.35 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29709995 | 0.72 | POLB (0.66) | POLBGAAGFERALDH1A1NPSR1 | |
| SCHEMBL12903976 | 0.72 | HTR6 (0.57) | POLBGAAGFERALDH1A1NPSR1 | |
| SCHEMBL312517 | 0.72 | POLB (0.66) | POLBGAAGFERALDH1A1NPSR1 | |
| SCHEMBL139251 | 0.71 | POLB (0.55) | POLBGAAGFERALDH1A1NPSR1 | |
| SCHEMBL28245930 | 0.69 | POLB (0.53) | POLBGAAGFERNPSR1HTR6 | |
| SCHEMBL9557407 | 0.69 | ALDH1A1 (0.43) | POLBGAAGFERALDH1A1NPSR1 | |
| SCHEMBL8080841 | 0.69 | HTR6 (0.72) | POLBGAAGFERALDH1A1NPSR1 | |
| SCHEMBL3145482 | 0.68 | POLB (0.51) | POLBGAAGFERNPSR1HTR6 | |
| SCHEMBL564663 | 0.68 | HTR6 (0.58) | POLBGAAGFERALDH1A1NPSR1 | |
| SCHEMBL28113141 | 0.68 | POLB (0.51) | POLBGAAGFERNPSR1HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0382628-B1 | Aminoalkoxylphenyl derivatives, process for their preparation and compositions containing them | SANOFI ELF (FR) | 1994-05-04 | — | — | EP | disclosed |
| EP-0382628-A1 | Aminoalkoxylphenyl derivatives, process for their preparation and compositions containing them | ELF SANOFI (FR) | 1990-08-16 | — | — | EP | disclosed |