Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC9 | O60706 | 12/20 | 0.38 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.33 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.33 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.33 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.32 |
| ▸ | BACE1 | P56817 | 2/20 | 0.32 |
| ▸ | ICMT | O60725 | 1/20 | 0.32 |
| ▸ | CTSD | P07339 | 1/20 | 0.32 |
| ▸ | CASP3 | P42574 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9779700 | 0.87 | ABCC9 (0.37) | ABCC9MALT1ABCB1BACE1CTSD | |
| SCHEMBL9374699 | 0.87 | ABCC9 (0.37) | ABCC9MALT1ABCB1BACE1CTSD | |
| SCHEMBL9372600 | 0.86 | ABCC9 (0.39) | ABCC9MALT1ABCB1 | |
| SCHEMBL9377387 | 0.85 | PDE4A (0.38) | ABCC9NPBWR1MCHR1BACE1ICMT | |
| SCHEMBL9373199 | 0.84 | ABCC9 (0.36) | ABCC9MALT1ABCB1BACE1CTSD | |
| SCHEMBL9378100 | 0.84 | ABCC9 (0.36) | ABCC9MALT1ABCB1 | |
| SCHEMBL9372849 | 0.84 | ABCC9 (0.36) | ABCC9MALT1ABCB1BACE1CTSD | |
| SCHEMBL9372282 | 0.83 | ABCC9 (0.38) | ABCC9MALT1ABCB1BACE1 | |
| SCHEMBL9779684 | 0.83 | ABCC9 (0.37) | ABCC9MALT1ABCB1BACE1ICMT | |
| SCHEMBL9379748 | 0.83 | ABCC9 (0.35) | ABCC9MALT1ABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0371312-B1 | Benzoxazine derivatives | MERCK PATENT GMBH (DE) | 1994-07-20 | — | — | EP | disclosed |
| US-5036068-A | Cardiovascular disorders | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1991-07-30 | — | — | US | disclosed |
| EP-0371312-A1 | Benzoxazine derivatives | MERCK PATENT GmbH (DE) | 1990-06-06 | — | — | EP | disclosed |