Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC9 | O60706 | 6/20 | 0.37 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.33 |
| ▸ | ABCB1 | P08183 | 4/20 | 0.32 |
| ▸ | ICMT | O60725 | 2/20 | 0.32 |
| ▸ | BACE1 | P56817 | 2/20 | 0.32 |
| ▸ | CTSD | P07339 | 1/20 | 0.32 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.32 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | NSD2 | O96028 | 1/20 | 0.32 |
| ▸ | CASP3 | P42574 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9373199 | 0.84 | ABCC9 (0.36) | ABCC9MALT1ABCB1BACE1CTSD | |
| SCHEMBL9376753 | 0.83 | ABCC9 (0.38) | ABCC9MALT1ABCB1ICMTBACE1 | |
| SCHEMBL9374699 | 0.83 | ABCC9 (0.37) | ABCC9MALT1ABCB1BACE1CTSD | |
| SCHEMBL9779700 | 0.83 | ABCC9 (0.37) | ABCC9MALT1ABCB1BACE1CTSD | |
| SCHEMBL9779701 | 0.82 | ABCC9 (0.37) | ABCC9MALT1ABCB1CASP3 | |
| SCHEMBL9377387 | 0.81 | PDE4A (0.38) | ABCC9ICMTBACE1 | |
| SCHEMBL8077047 | 0.80 | ABCC9 (0.37) | ABCC9MALT1ABCB1ICMTDDB1 | |
| SCHEMBL8085075 | 0.80 | PDE4A (0.41) | ABCC9MALT1ABCB1DDB1CRBN | |
| SCHEMBL9779788 | 0.80 | ABCC9 (0.43) | ABCC9MALT1ABCB1CASP3 | |
| SCHEMBL9378100 | 0.80 | ABCC9 (0.36) | ABCC9MALT1ABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5036068-A | Cardiovascular disorders | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1991-07-30 | — | — | US | disclosed |
| EP-0371312-A1 | Benzoxazine derivatives | MERCK PATENT GmbH (DE) | 1990-06-06 | — | — | EP | disclosed |