Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.38 |
| ▸ | CASP1 | P29466 | 3/20 | 0.38 |
| ▸ | CASP7 | P55210 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | HBB | P68871 | 2/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.38 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 4/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2096786 | 0.83 | ALDH1A1 (0.46) | ALDH1A1CYP3A4HSD17B10ALOX15CASP1 | |
| SCHEMBL29434206 | 0.83 | ALDH1A1 (0.46) | ALDH1A1CYP3A4HSD17B10ALOX15CASP1 | |
| SCHEMBL20610260 | 0.78 | ALDH1A1 (0.42) | ALDH1A1CYP3A4HSD17B10ALOX15CASP1 | |
| SCHEMBL29954537 | 0.77 | TDP1 (0.46) | IDO1ALDH1A1CYP3A4HSD17B10ALOX15 | |
| SCHEMBL1767506 | 0.77 | TDP1 (0.46) | IDO1ALDH1A1CYP3A4HSD17B10ALOX15 | |
| SCHEMBL15566154 | 0.77 | PTK2 (0.35) | ALDH1A1 | |
| SCHEMBL15565870 | 0.75 | PTK2 (0.41) | ALDH1A1 | |
| SCHEMBL29391862 | 0.74 | CYP3A4 (0.55) | IDO1ALDH1A1CYP3A4HSD17B10ALOX15 | |
| SCHEMBL139321 | 0.74 | CYP3A4 (0.55) | IDO1ALDH1A1CYP3A4HSD17B10ALOX15 | |
| SCHEMBL25216045 | 0.74 | ALDH1A1 (0.48) | ALDH1A1HSD17B10CASP1TDP1HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023120315-A1 | ORGANIC COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT | キヤノン株式会社 | 2023-06-29 | — | — | WO | disclosed |
| US-8921554-B2 | Substituted 1,2-azaborine heterocycles | STATE OF OREGON ACTING BY AND THROUGH THE STATE BOARD OF HIGHER EDUCATION ON BEHALF OF THE UNIVERSITY OF OREGON (US) | 2014-12-30 | — | — | US | disclosed |
| US-8921554-B2 | Substituted 1,2-azaborine heterocycles | STATE OF OREGON ACTING BY AND THROUGH THE STATE BOARD OF HIGHER EDUCATION ON BEHALF OF THE UNIVERSITY OF OREGON (US) | 2014-12-30 | — | — | US | disclosed |
| US-8921554-B2 | Substituted 1,2-azaborine heterocycles | STATE OF OREGON ACTING BY AND THROUGH THE STATE BOARD OF HIGHER EDUCATION ON BEHALF OF THE UNIVERSITY OF OREGON (US) | 2014-12-30 | — | — | US | disclosed |
| WO-2014025424-A2 | BORON-NITROGEN-CONTAINING ACENE COMPOUNDS AND THEIR PREPARATION | STATE OF OREGON ACTING BY & THROUGH THE STATE BOARD OF HIGHER EDUC. ON BEHALF OF THE UNIV. OF OREGON (US) | 2014-02-13 | — | — | WO | disclosed |
| EP-2459573-A1 | SUBSTITUTED 1,2-AZABORINE HETEROCYCLES | State of Oregon acting by & through the State Board of Higher Eduction on behalf of the University of Oregon (US) | 2012-06-06 | — | — | EP | disclosed |
| WO-2011017129-A1 | SUBSTITUTED 1,2-AZABORINE HETEROCYCLES | STATE OF OREGON ON BEHALF OF THE UNIVERSITY OF OREGON (US) | 2011-02-10 | — | — | WO | disclosed |
| WO-2011017129-A1 | SUBSTITUTED 1,2-AZABORINE HETEROCYCLES | STATE OF OREGON ON BEHALF OF THE UNIVERSITY OF OREGON (US) | 2011-02-10 | — | — | WO | disclosed |
| US-20110021735-A1 | SUBSTITUTED 1,2-AZABORINE HETEROCYCLES | STATE OF OREGON ACTING BY AND THROUGH THE STATE BOARD OF HIGHER EDUCATION ON BEHALF OF THE UNIVERSITY OF OREGON | 2011-01-27 | — | — | US | disclosed |
| US-20110021735-A1 | SUBSTITUTED 1,2-AZABORINE HETEROCYCLES | STATE OF OREGON ACTING BY AND THROUGH THE STATE BOARD OF HIGHER EDUCATION ON BEHALF OF THE UNIVERSITY OF OREGON | 2011-01-27 | — | — | US | disclosed |
| US-20110021735-A1 | SUBSTITUTED 1,2-AZABORINE HETEROCYCLES | STATE OF OREGON ACTING BY AND THROUGH THE STATE BOARD OF HIGHER EDUCATION ON BEHALF OF THE UNIVERSITY OF OREGON | 2011-01-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110021735-A1 | SUBSTITUTED 1,2-AZABORINE HETEROCYCLES | AZI2, CYP1B1, NMBR | IDO1 705/4885ALDH1A1 1543/4885CYP3A4 178/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.