Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | IDO1 | P14902 | 1/20 | 0.45 |
| ▸ | ERN1 | O75460 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
| ▸ | HBB | P68871 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1767506 | 1.00 | TDP1 (0.46) | TDP1LMNAKMT2AMEN1THRB | |
| SCHEMBL5751119 | 0.96 | ALDH1A1 (0.45) | TDP1LMNAKMT2AMEN1THRB | |
| SCHEMBL652955 | 0.83 | LMNA (0.58) | TDP1LMNAKMT2AMEN1THRB | |
| SCHEMBL29364404 | 0.83 | LMNA (0.58) | TDP1LMNAKMT2AMEN1THRB | |
| Benzo[D]Isoxazole SCHEMBL28970691 | 0.80 | POLB (0.38) | TDP1LMNAKMT2AMEN1THRB | |
| SCHEMBL986911 | 0.78 | TDP1 (0.52) | TDP1LMNAKMT2AMEN1THRB | |
| SCHEMBL30402244 | 0.78 | TDP1 (0.52) | TDP1LMNAKMT2AMEN1THRB | |
| SCHEMBL547777 | 0.78 | TDP1 (0.52) | TDP1LMNAKMT2AMEN1THRB | |
| SCHEMBL937705 | 0.77 | IDO1 (0.41) | TDP1LMNAKMT2AMEN1IDO1 | |
| SCHEMBL8024070 | 0.77 | TDP1 (0.40) | TDP1LMNAKMT2AMEN1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |