Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | RARA | P10276 | 1/20 | 0.31 |
| ▸ | RARB | P10826 | 1/20 | 0.31 |
| ▸ | RARG | P13631 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8793143 | 0.88 | SMN1; SMN2 (0.33) | SMN1; SMN2 | |
| SCHEMBL8793777 | 0.86 | SMN1; SMN2 (0.33) | SMN1; SMN2RARARARBRARG | |
| SCHEMBL8795130 | 0.85 | ABL1 (0.32) | SMN1; SMN2 | |
| SCHEMBL8795134 | 0.85 | RARA (0.31) | SMN1; SMN2RARARARBRARG | |
| SCHEMBL9378364 | 0.84 | LMNA (0.34) | RARARARBRARG | |
| SCHEMBL8794636 | 0.82 | SMN1; SMN2 (0.34) | SMN1; SMN2NPC1RAB9A | |
| SCHEMBL8794583 | 0.80 | SMN1; SMN2 (0.30) | SMN1; SMN2 | |
| SCHEMBL9381836 | 0.80 | PSEN1 (0.36) | — | |
| SCHEMBL9378940 | 0.80 | SMN1; SMN2 (0.30) | SMN1; SMN2 | |
| SCHEMBL9377533 | 0.80 | RARA (0.31) | RARARARBRARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0586405-A1 | NOVEL 2H-BENZO b]PYRANE DERIVATIVES SUBSTITUTED IN THE 4 POSITION BY ARYL OR N-HETEROARYL, PROCESS FOR PRODUCING THEM AND PREPARATIONS CONTAINING THE COMPOUNDS. | BEIERSDORF LILLY GMBH (DE) | 1994-03-16 | — | — | EP | disclosed |
| WO-1992020671-A1 | NOVEL 2H-BENZO[b]PYRANE DERIVATIVES SUBSTITUTED IN THE 4 POSITION BY ARYL OR N-HETEROARYL, PROCESS FOR PRODUCING THEM AND PREPARATIONS CONTAINING THE COMPOUNDS | BEIERSDORF-LILLY GMBH (DE) | 1992-11-26 | — | — | WO | disclosed |