Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 9/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | GLA | P06280 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | PGAM1 | P18669 | 1/20 | 0.52 |
| ▸ | CASP1 | P29466 | 1/20 | 0.52 |
| ▸ | CASP7 | P55210 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.51 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.51 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.51 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.51 |
| ▸ | MGAM | O43451 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | SI | P14410 | 1/20 | 0.44 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9375977 | 0.83 | KDM4E (0.56) | MAOAKDM4EALDH1A1GLACYP3A4 | |
| SCHEMBL18242476 | 0.80 | MAOA (0.59) | MAOAKDM4EALDH1A1GLACYP3A4 | |
| SCHEMBL13359234 | 0.80 | MAOA (0.64) | MAOAKDM4EALDH1A1GLACYP3A4 | |
| SCHEMBL7943748 | 0.79 | MAOA (0.57) | MAOAKDM4EALDH1A1GLACYP3A4 | |
| SCHEMBL9376908 | 0.79 | MAOA (0.57) | MAOAKDM4EALDH1A1GLACYP3A4 | |
| SCHEMBL5425706 | 0.76 | MAOA (0.54) | MAOAKDM4EALDH1A1GLACYP3A4 | |
| SCHEMBL18242380 | 0.76 | MAOA (0.54) | MAOAKDM4EALDH1A1GLACYP3A4 | |
| SCHEMBL10452807 | 0.76 | MAOA (0.57) | MAOAKDM4EALDH1A1GLACYP3A4 | |
| SCHEMBL7140586 | 0.75 | MAOA (0.57) | MAOAKDM4EALDH1A1GLACYP3A4 | |
| SCHEMBL28194247 | 0.75 | MAOA (0.53) | MAOAKDM4EALDH1A1GLACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0278176-B1 | Compounds having antitumour and antibacterial properties | WARNER LAMBERT CO (US) | 1994-03-09 | — | — | EP | disclosed |
| US-5281620-A | Alkyl substituted xanthenone-4-acetic acid | CANCER RESEARCH CAMPAIGN TECHNOLOGY LIMITED (GB) | 1994-01-25 | — | — | US | disclosed |
| EP-0278176-A2 | Compounds having antitumour and antibacterial properties | WARNER-LAMBERT COMPANY (US) | 1988-08-17 | — | — | EP | disclosed |