SCHEMBL7140586

SCHEMBL7140586

O=C(O)Cc1cccc2oc3ccccc3c(=O)c12

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 4/20 0.57
KDM4E B2RXH2 4/20 0.52
GLA P06280 2/20 0.52
ALDH1A1 P00352 1/20 0.52
CYP3A4 P08684 1/20 0.52
MAPT P10636 1/20 0.52
HPGD P15428 1/20 0.52
PGAM1 P18669 1/20 0.52
CASP1 P29466 1/20 0.52
CASP7 P55210 1/20 0.52
SMN1; SMN2 Q16637 1/20 0.52
HSD17B10 Q99714 1/20 0.52
TDP1 Q9NUW8 1/20 0.51
CYP17A1 P05093 1/20 0.51
CYP19A1 P11511 1/20 0.51
CYP11B1 P15538 1/20 0.51
CYP11B2 P19099 1/20 0.51
TTR P02766 2/20 0.48
GAA P10253 2/20 0.48
MGAM O43451 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9367069 0.89 TDP1 (0.56) MAOAKDM4EGLAALDH1A1CYP3A4
SCHEMBL9738575 0.87 MAOA (0.53) MAOAKDM4EGLAALDH1A1CYP3A4
SCHEMBL27726953 0.86 MAOA (0.55) MAOAKDM4EGLAALDH1A1CYP3A4
SCHEMBL13359234 0.83 MAOA (0.64) MAOAKDM4EGLAALDH1A1CYP3A4
SCHEMBL29975151 0.83 KDM4E (0.71) MAOAKDM4EGLAALDH1A1CYP3A4
SCHEMBL107952 0.83 KDM4E (0.71) MAOAKDM4EGLAALDH1A1CYP3A4
SCHEMBL27860391 0.80 KDM4E (0.56) MAOAKDM4EGLAALDH1A1CYP3A4
SCHEMBL8649540 0.80 MAOA (0.46) MAOAKDM4EGLAALDH1A1CYP3A4
SCHEMBL18242476 0.80 MAOA (0.59) MAOAKDM4EGLAALDH1A1CYP3A4
SCHEMBL5425706 0.79 MAOA (0.54) MAOAKDM4EGLAALDH1A1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9855734-B2 Wafer processing method SEKISUI CHEMICAL CO., LTD. (JP) 2018-01-02 US disclosed
CN-104520974-B The processing method of wafer SEKISUI CHEMICAL CO.,LTD. (JP) 2016-02-10 CN disclosed
US-20150217552-A1 WAFER PROCESSING METHOD SEKISUI CHEMICAL CO., LTD. (JP) 2015-08-06 US disclosed
CN-104541356-A Processing method for wafer SEKISUI CHEMICAL CO LTD 2015-04-22 CN disclosed
CN-104520974-A Wafer processing method SEKISUI CHEMICAL CO LTD 2015-04-15 CN disclosed
US-6514983-B1 Inhibitors of the nucleic enzyme poly(adenosine 5'-diphospho-ribose)polymerase GUILFORD PHARMACEUTICALS INC. 2003-02-04 US disclosed
US-6306889-B1 FUSED HETEROCYCLIC DRUGS FOR CARDIOVASCULAR DISORDERS GUILFORD PHARMACEUTICALS INC. 2001-10-23 US disclosed
EP-1019409-A1 POLY(ADP-RIBOSE) POLYMERASE (\"PARP\") INHIBITORS, METHODS AND PHARMACEUTICAL COMPOSITIONS FOR TREATING NEURAL OR CARDIOVASCULAR TISSUE DAMAGE GUILFORD PHARMACEUTICALS INC. (US) 2000-07-19 EP disclosed
WO-1999011645-A1 POLY(ADP-RIBOSE) POLYMERASE ('PARP') INHIBITORS, METHODS AND PHARMACEUTICAL COMPOSITIONS FOR TREATING NEURAL OR CARDIOVASCULAR TISSUE DAMAGE GUILFORD PHARMACEUTICALS INC. (US) 1999-03-11 WO disclosed
EP-0278176-B1 Compounds having antitumour and antibacterial properties WARNER LAMBERT CO (US) 1994-03-09 EP disclosed
US-5281620-A Alkyl substituted xanthenone-4-acetic acid CANCER RESEARCH CAMPAIGN TECHNOLOGY LIMITED (GB) 1994-01-25 US disclosed
EP-0278176-A2 Compounds having antitumour and antibacterial properties WARNER-LAMBERT COMPANY (US) 1988-08-17 EP disclosed