SCHEMBL9378043

SCHEMBL9378043

O=C(Oc1cc[c]cc1)OC(Cl)(Cl)CCl

nearest known ligand 0.37

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
ELANE P08246 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9375710 0.80
SCHEMBL486023 0.75 ELANE (0.62) ELANE
SCHEMBL11423460 0.75 BCL9 (0.49)
SCHEMBL9378048 0.75 CHRM2 (0.31) ELANE
SCHEMBL9530245 0.72
SCHEMBL583307 0.71
SCHEMBL11230246 0.71 KMT2A (0.39) ELANE
SCHEMBL11333740 0.70 ALDH1A1 (0.39)
SCHEMBL2236908 0.69 KMT2A (0.44) ELANE
SCHEMBL8942876 0.69 TDP1 (0.44) ELANE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5294737-A Hydrolysis, cyclization, condensation THE RESEARCH FOUNDATION STATE UNIVERSITY OF NEW YORK (US) 1994-03-15 US claimed