Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.43 |
| ▸ | RAB9A | P51151 | 5/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.42 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9371669 | 0.99 | SMN1; SMN2 (0.42) | SMN1; SMN2RAB9AADORA3ADORA2AADORA2B | |
| SCHEMBL9372186 | 0.86 | SMN1; SMN2 (0.43) | SMN1; SMN2RAB9AADORA3ADORA2AADORA2B | |
| SCHEMBL9373896 | 0.82 | SMN1; SMN2 (0.47) | SMN1; SMN2RAB9AADORA3ADORA2AADORA2B | |
| SCHEMBL10449776 | 0.82 | SMN1; SMN2 (0.47) | SMN1; SMN2RAB9AADORA3ADORA2AADORA2B | |
| SCHEMBL27339512 | 0.81 | RAB9A (0.59) | SMN1; SMN2RAB9AKDM4ENPC1LMNA | |
| Hydrochloric Acid SCHEMBL9373000 | 0.80 | RAB9A (0.57) | SMN1; SMN2RAB9AKDM4ENPC1LMNA | |
| SCHEMBL27319307 | 0.72 | SMN1; SMN2 (0.43) | SMN1; SMN2RAB9AKDM4ENPC1LMNA | |
| SCHEMBL8878334 | 0.70 | SMN1; SMN2 (0.65) | SMN1; SMN2RAB9AADORA3ADORA2AADORA2B | |
| SCHEMBL27321322 | 0.69 | PTPN1 (0.55) | SMN1; SMN2RAB9AKDM4EKMT2APTPN1 | |
| Hydrochloric Acid SCHEMBL27339511 | 0.69 | RAB9A (0.45) | SMN1; SMN2RAB9AKDM4ENPC1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0399645-B1 | Tetrahydropyranyl derivatives, process for their preparation and pharmaceutical or veterinary compositions containing them | BEECHAM GROUP PLC (GB) | 1994-11-09 | — | — | EP | disclosed |