Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | AGER | Q15109 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | SLC11A2 | P49281 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9379022 | 0.77 | LOX (0.54) | MEN1LMNAMAPTKMT2AKDM4E | |
| SCHEMBL9379932 | 0.75 | MEN1 (0.64) | P4HTMNPC1RAB9ACYP1A2CYP2D6 | |
| SCHEMBL9383881 | 0.74 | KDM4E (0.45) | CYP1A2CYP2C9MEN1MAPTKMT2A | |
| SCHEMBL9379816 | 0.74 | VHL (0.46) | P4HTMNPC1RAB9ACYP2C9MEN1 | |
| SCHEMBL9379617 | 0.74 | CES2 (0.39) | NPC1RAB9ACYP1A2MEN1MAPT | |
| SCHEMBL9379150 | 0.73 | KDM4E (0.56) | NPC1RAB9AMEN1MAPTKMT2A | |
| SCHEMBL9383599 | 0.72 | P4HTM (0.45) | P4HTMCYP1A2CYP2C9MEN1LMNA | |
| SCHEMBL9378591 | 0.72 | KDM4E (0.46) | NPC1RAB9ACYP1A2MEN1LMNA | |
| SCHEMBL9385752 | 0.72 | KDM4E (0.46) | NPC1RAB9ACYP1A2CYP2C9MEN1 | |
| SCHEMBL9383573 | 0.72 | KDM4E (0.38) | CYP1A2CYP2C9MEN1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0269030-B1 | Lipid-peroxide formation inhibiting composition and novel compounds useful therefor | MITSUBISHI CHEM IND (JP) | 1994-05-04 | — | — | EP | disclosed |
| US-5089515-A | Antiischemic agents; pyrazolone compounds | MITSUBISHI KASEI CORPORATION (JP) | 1992-02-18 | — | — | US | disclosed |
| US-4990619-A | Cardiovascular disorders, antiischemic agents | MITSUBISHI KASEI CORPORATION (JP) | 1991-02-05 | — | — | US | disclosed |
| US-4906644-A | Lipid-peroxide formation inhibiting composition and novel compounds useful therefor | MITSUBISHI KASEI CORPORATION (JP) | 1990-03-06 | — | — | US | disclosed |
| EP-0269030-A2 | Lipid-peroxide formation inhibiting composition and novel compounds useful therefor | MITSUBISHI KASEI CORPORATION (JP) | 1988-06-01 | — | — | EP | disclosed |