SCHEMBL937880

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL940269	0.92	SMN1; SMN2 (0.38)	MAPTLMNAKMT2AMEN1RAD52
	SCHEMBL939371	0.84	MAPT (0.38)	MAPTPPARGNCOA2NCOA1NCOA3
	SCHEMBL11947888	0.83	SMN1; SMN2 (0.37)	MAPTLMNAKMT2AMEN1RAD52
	SCHEMBL13050516	0.83	SMN1; SMN2 (0.37)	MAPTCYP2C9LMNAKMT2AMEN1
	SCHEMBL11947880	0.77	PARP1 (0.42)	MAPTCYP2C9LMNAKMT2AALDH1A1
	SCHEMBL937879	0.77	LMNA (0.43)	MAPTPPARGNCOA2NCOA1NCOA3
	SCHEMBL938881	0.77	CYP3A4 (0.47)	CYP2C9KMT2AALDH1A1HPGDSMN1; SMN2
	SCHEMBL938351	0.76	CYP3A4 (0.46)	CYP2C9ALDH1A1HPGDSMN1; SMN2MAPK1
	SCHEMBL939382	0.76	SMN1; SMN2 (0.38)	MAPTLMNAKMT2AMEN1SMN1; SMN2
	SCHEMBL938962	0.73	CYP2C9 (0.38)	MAPTCYP2C9LMNAKMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.