Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 9/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | PREP | P48147 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28553183 | 0.78 | MAPK14 (0.37) | MAPK14ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL29387994 | 0.78 | MAPK14 (0.37) | MAPK14ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL92683 | 0.76 | MAPK14 (0.37) | MAPK14ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL5621937 | 0.74 | MAPK14 (0.36) | MAPK14ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL28553182 | 0.74 | MAPK14 (0.36) | MAPK14ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL18672266 | 0.68 | SMN1; SMN2 (0.53) | MAPK14ALDH1A1MEN1KMT2ARAB9A | |
| SCHEMBL27704723 | 0.68 | MAPK14 (0.33) | MAPK14 | |
| SCHEMBL16901965 | 0.67 | SMN1; SMN2 (0.46) | MAPK14ALDH1A1MEN1KMT2ARAB9A | |
| SCHEMBL18672246 | 0.66 | SMN1; SMN2 (0.48) | MAPK14ALDH1A1MEN1KMT2ARAB9A | |
| SCHEMBL15565769 | 0.66 | BPTF (0.46) | MAPK14RAB9ANPC1POLBGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0302346-B1 | Pyridazinone derivatives and compositions for controlling and/or preventing insect pests | NISSAN CHEMICAL IND LTD (JP) | 1994-12-28 | — | — | EP | disclosed |
| US-4945091-A | INSECTICIDES, ACARACIDES, NEMATOCIDES | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 1990-07-31 | — | — | US | disclosed |
| EP-0302346-A2 | Pyridazinone derivatives and compositions for controlling and/or preventing insect pests | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1989-02-08 | — | — | EP | disclosed |