SCHEMBL92683

SCHEMBL92683

CC(C)(Cl)Cn1ncc(OCc2ccc(I)nc2)c(Cl)c1=O

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPK14 Q16539 6/20 0.37
▸ HTT P42858 6/20 0.36
▸ ALDH1A1 P00352 6/20 0.36
▸ SMN1; SMN2 Q16637 3/20 0.36
▸ NPSR1 Q6W5P4 4/20 0.33
▸ RAB9A P51151 4/20 0.33
▸ MITF O75030 2/20 0.33
▸ PKM P14618 1/20 0.33
▸ NPC1 O15118 3/20 0.33
▸ NR2E3 Q9Y5X4 1/20 0.32
▸ MAPT P10636 3/20 0.32
▸ POLB P06746 2/20 0.32
▸ MEN1 O00255 2/20 0.31
▸ KMT2A Q03164 2/20 0.31
▸ BRD4 O60885 1/20 0.31
▸ BPTF Q12830 1/20 0.31
▸ GAA P10253 1/20 0.31
▸ NPBWR1 P48145 1/20 0.31
▸ LMNA P02545 3/20 0.31
▸ GALR3 O60755 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5621937 0.91 MAPK14 (0.36) MAPK14HTTALDH1A1SMN1; SMN2NPSR1
SCHEMBL27704723 0.90 MAPK14 (0.33) MAPK14
SCHEMBL31130800 0.89 MAPK14 (0.36) MAPK14HTTALDH1A1SMN1; SMN2NPSR1
SCHEMBL29546003 0.86 MAPK14 (0.33) MAPK14NR2E3
SCHEMBL2581086 0.85 NPSR1 (0.35) MAPK14HTTALDH1A1SMN1; SMN2NPSR1
SCHEMBL28553182 0.81 MAPK14 (0.36) MAPK14HTTALDH1A1SMN1; SMN2NPSR1
SCHEMBL9377376 0.80 APP (0.34) MAPK14HTTALDH1A1SMN1; SMN2NPSR1
SCHEMBL9373345 0.80 MAPK14 (0.38) MAPK14HTTALDH1A1SMN1; SMN2NR2E3
SCHEMBL28635592 0.79 MCHR1 (0.43) —
SCHEMBL29387994 0.78 MAPK14 (0.37) MAPK14ALDH1A1RAB9ANPC1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1766 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260137082-A1 FUNGICIDAL COMPOSITIONS COMPRISING FLUDIOXONIL SYNGENTA CROP PROTECTION AG (CH) 2026-05-21 — — US claimed
US-12279611-B2 Method for controlling insects where an alkoxylated glycerol is applied to soil BASF SE (DE) 2025-04-22 — — US claimed
US-20250017207-A1 FUNGICIDAL COMPOSITIONS SYNGENTA CROP PROTECTION AG (CH) 2025-01-16 — — US claimed
EP-4422402-A1 FUNGICIDAL COMPOSITIONS COMPRISING FLUDIOXONIL Syngenta Crop Protection AG (CH) 2024-09-04 — — EP claimed
EP-4422404-A1 FUNGICIDAL COMPOSITIONS Syngenta Crop Protection AG (CH) 2024-09-04 — — EP claimed
CN-118368985-A Fungicidal compositions 先正达农作物保护股份公司 2024-07-19 — — CN claimed
CN-118019451-A Fungicidal compositions comprising fludioxonil 先正达农作物保护股份公司 2024-05-10 — — CN claimed
WO-2023072784-A1 FUNGICIDAL COMPOSITIONS COMPRISING FLUDIOXONIL SYNGENTA CROP PROTECTION AG (CH) 2023-05-04 — — WO claimed
WO-2023072785-A1 FUNGICIDAL COMPOSITIONS SYNGENTA CROP PROTECTION AG (CH) 2023-05-04 — — WO claimed
EP-3490378-B1 A METHOD FOR CONTROLLING INSECTS WHERE AN ALKOXYLATED GLYCEROL IS APPLIED TO SOIL BASF SE (DE) 2021-10-13 — — EP claimed
WO-2006026598-A1 METHOPRENE FORMULATIONS FOR THE CONTROL OF TICK INFESTATIONS MERIAL LIMITED (US) 2006-03-09 — — WO claimed
US-20060046988-A1 Methoprene formulations for the control of tick infestations MERIAL LIMITED 2006-03-02 — — US claimed
WO-2005063015-A1 STABILIZED FORMULATION OF IVERMERCTIN FEED PREMIX MERIAL LIMITED (US) 2005-07-14 — — WO claimed
US-20050136087-A1 Stabilized formulation of ivermectin feed premix with an extended shelf life and method of making the same MERIAL, INC. 2005-06-23 — — US claimed
US-20050137244-A1 Topical formulations comprising 1-N-arylpyrazole derivatives and amitraz MERIAL, INC. 2005-06-23 — — US claimed
US-20040167175-A1 1-N-arylpyrazole derivatives in prevention of arthropod-borne and mosquito-borne diseases MERIAL LIMITED, REGISTERED IN ENGLAND AND WALES NO. 3332751 AND DOMESTICATED IN DELAWARE, USA AS MERIAL LLC, WITH A PLACE OF BUSINESS AT 3239 SATELLITE BLVD., DULUTH, GA 30096-4640 (GB) 2004-08-26 — — US claimed
US-6685954-B2 FOR APPLICATION TO SKIN MERIAL (FR) 2004-02-03 — — US claimed
US-20020090387-A1 Insecticidal combination to control mammal fleas in particular fleas in particular fleas on cats and dogs JEANNIN PHILIPPE (FR) 2002-07-11 — — US claimed
US-6096329-A Insecticidal combination to control mammal fleas, in particular fleas on cats and dogs MERIAL (FR) 2000-08-01 — — US claimed
WO-1997036485-A1 INSECTICIDAL COMBINATION EFFECTIVE AGAINST FLEAS ON MAMMALS, PARTICULARLY CATS AND DOGS MERIAL (FR) 1997-10-09 — — WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040167175-A1 1-N-arylpyrazole derivatives in prevention of arthropod-borne and mosquito-borne diseases NAT1, PON1, AANAT MAPK14 3211/4885HTT 737/4885ALDH1A1 177/4885
US-20250017207-A1 FUNGICIDAL COMPOSITIONS CYP51A1, BROX, DPM1 MAPK14 4440/4885HTT 1523/4885ALDH1A1 1605/4885
US-20260137082-A1 FUNGICIDAL COMPOSITIONS COMPRISING FLUDIOXONIL NOTUM, CTRL, BROX MAPK14 3913/4885HTT 2629/4885ALDH1A1 2077/4885
US-20050137244-A1 Topical formulations comprising 1-N-arylpyrazole derivatives and amitraz MGAT2, MGAT1, MIF MAPK14 2754/4885HTT 2088/4885ALDH1A1 1568/4885
US-20020090387-A1 Insecticidal combination to control mammal fleas in particular fleas in particular fleas on cats and dogs CUTA, IGF1R, FIBP MAPK14 1957/4885HTT 2275/4885ALDH1A1 3353/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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