Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSV | O60911 | 3/20 | 0.43 |
| ▸ | CTSL | P07711 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.42 |
| ▸ | LMNA | P02545 | 5/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.42 |
| ▸ | NPC1 | O15118 | 6/20 | 0.42 |
| ▸ | RAB9A | P51151 | 6/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA5A | P35218 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9379483 | 1.00 | CTSV (0.43) | CTSVCTSLALDH1A1LMNACYP1A2 | |
| SCHEMBL9380386 | 0.93 | MAPT (0.39) | ALDH1A1LMNACYP1A2CYP2D6CYP2C9 | |
| SCHEMBL9380389 | 0.93 | MAPT (0.39) | ALDH1A1LMNACYP1A2CYP2D6CYP2C9 | |
| SCHEMBL9378625 | 0.89 | SMN1; SMN2 (0.51) | CTSVCTSLALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL9378630 | 0.89 | SMN1; SMN2 (0.51) | CTSVCTSLALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL9375758 | 0.82 | TLR9 (0.41) | ALDH1A1LMNASMN1; SMN2NPC1RAB9A | |
| SCHEMBL9375752 | 0.82 | TLR9 (0.41) | ALDH1A1LMNASMN1; SMN2NPC1RAB9A | |
| SCHEMBL9381202 | 0.81 | MAPT (0.44) | CTSVCTSLALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL9381205 | 0.81 | MAPT (0.44) | CTSVCTSLALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL4645564 | 0.76 | ALDH1A1 (0.62) | CTSVCTSLALDH1A1LMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0356234-B1 | New Benzazole compounds, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO (JP) | 1994-05-11 | — | — | EP | disclosed |
| US-5047411-A | Antiulcer Agents, H2-Receptor Antagonists | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-09-10 | — | — | US | disclosed |
| EP-0356234-A2 | New Benzazole compounds, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1990-02-28 | — | — | EP | disclosed |