SCHEMBL9379693

SCHEMBL9379693

O=CC(=O)C12CCCN(CC1)C2

nearest known ligand 0.56

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CHRM2 P08172 2/20 0.41
CHRM4 P08173 2/20 0.41
CHRM1 P11229 2/20 0.41
CHRM3 P20309 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bromide SCHEMBL9293775 0.98 CHRM2 (0.40) CHRM2CHRM4CHRM1CHRM3
SCHEMBL9376959 0.92 CHRM2 (0.34) CHRM2CHRM4CHRM1CHRM3
Bromide SCHEMBL9293969 0.90 CHRM2 (0.33) CHRM2CHRM4CHRM1CHRM3
SCHEMBL2821565 0.80 CHRM2 (0.38) CHRM2CHRM4CHRM1CHRM3
SCHEMBL2821568 0.80 CHRM2 (0.38) CHRM2CHRM4CHRM1CHRM3
SCHEMBL205297 0.78 CHRM2 (0.44) CHRM2CHRM4CHRM1CHRM3
SCHEMBL31731969 0.78 CHRM2 (0.44) CHRM2CHRM4CHRM1CHRM3
SCHEMBL8557075 0.76 CHRM2 (0.46) CHRM2CHRM4CHRM1CHRM3
Hydrochloric Acid SCHEMBL2421629 0.76 CHRM2 (0.42) CHRM2CHRM4CHRM1CHRM3
SCHEMBL9049033 0.76 CHRM2 (0.42) CHRM2CHRM4CHRM1CHRM3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0594605-A1 1-AZABICYCLIC COMPOUNDS, PROCESSES AND PHARMACEUTICAL COMPOSITONS CONTAINING THEM Beecham Group p.l.c. (GB) 1994-05-04 EP claimed
WO-1991013885-A1 1-AZABICYCLIC COMPOUNDS, PROCESSES AND PHARMACEUTICAL COMPOSITONS CONTAINING THEM BEECHAM GROUP PLC (GB) 1991-09-19 WO claimed