Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 2/20 | 0.42 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9458387 | 0.96 | CHRM2 (0.38) | CHRM2CHRM4CHRM1CHRM3PKM | |
| SCHEMBL9050123 | 0.91 | CHRM2 (0.36) | CHRM2CHRM4CHRM1CHRM3PKM | |
| SCHEMBL8790912 | 0.87 | CHRM2 (0.34) | CHRM2CHRM4CHRM1CHRM3PKM | |
| SCHEMBL205297 | 0.81 | CHRM2 (0.44) | CHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL31731969 | 0.81 | CHRM2 (0.44) | CHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL205952 | 0.79 | CHRM2 (0.42) | CHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL8557075 | 0.79 | CHRM2 (0.46) | CHRM2CHRM4CHRM1CHRM3 | |
| Hydrochloric Acid SCHEMBL2421629 | 0.79 | CHRM2 (0.42) | CHRM2CHRM4CHRM1CHRM3 | |
| Hydrochloric Acid SCHEMBL6990830 | 0.78 | CHRM2 (0.41) | CHRM2CHRM4CHRM1CHRM3 | |
| Bromide SCHEMBL8556591 | 0.77 | CHRM2 (0.39) | CHRM2CHRM4CHRM1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0287356-B1 | Bridgehead substituted azabicyclic derivatives | BEECHAM GROUP PLC (GB) | 1996-01-24 | — | — | EP | claimed |
| EP-0287356-B1 | Bridgehead substituted azabicyclic derivatives | BEECHAM GROUP PLC (GB) | 1996-01-24 | — | — | EP | disclosed |
| US-5132316-A | Cognition activators | BEECHAM GROUP P.L.C. (GB) | 1992-07-21 | — | — | US | disclosed |
| US-4971975-A | TREATMENT OF DEMENTIA; AZABICYCLOOCTANE COMPOUNDS | BEECHAM GROUP PLC (GB) | 1990-11-20 | — | — | US | disclosed |
| EP-0287356-A2 | Bridgehead substituted azabicyclic derivatives | BEECHAM GROUP PLC (GB) | 1988-10-19 | — | — | EP | disclosed |