Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.74 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.56 |
| ▸ | HTR4 | Q13639 | 3/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.56 |
| ▸ | HTR3A | P46098 | 2/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | GLA | P06280 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL384749 | 0.85 | GAA (1.00) | GAACYP3A4HTR4CYP2D6HTR3A | |
| Hydrochloric Acid SCHEMBL7405359 | 0.84 | GAA (0.97) | GAACYP3A4HTR4CYP2D6HTR3A | |
| SCHEMBL8292456 | 0.84 | GAA (0.79) | GAACYP3A4HTR4CYP2D6HTR3A | |
| SCHEMBL725809 | 0.80 | GAA (0.73) | GAACYP3A4HTR4CYP2D6HTR3A | |
| SCHEMBL99019 | 0.80 | GAA (0.73) | GAACYP3A4HTR4CYP2D6HTR3A | |
| SCHEMBL7280230 | 0.80 | GAA (0.73) | GAACYP3A4HTR4CYP2D6HTR3A | |
| SCHEMBL7351910 | 0.80 | GAA (0.73) | GAACYP3A4HTR4CYP2D6HTR3A | |
| SCHEMBL1744462 | 0.80 | GAA (0.72) | GAACYP3A4HTR4CYP2D6HTR3A | |
| SCHEMBL1707866 | 0.79 | NPC1 (0.78) | GAACYP3A4HTR4CYP2D6HTR3A | |
| Hydrochloric Acid SCHEMBL724940 | 0.79 | GAA (0.71) | GAACYP3A4HTR4CYP2D6HTR3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0581777-A1 | STEREOSELECTIVE PREPARATION OF SUBSTITUTED PIPERIDINES | PFIZER INC. (US) | 1994-02-09 | — | — | EP | disclosed |
| WO-1992017449-A1 | STEREOSELECTIVE PREPARATION OF SUBSTITUTED PIPERIDINES | PFIZER INC. (US) | 1992-10-15 | — | — | WO | disclosed |