Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9381845 | 0.88 | ALOX5 (0.32) | ALOX5 | |
| SCHEMBL9385312 | 0.88 | ALOX5 (0.32) | ALOX5 | |
| SCHEMBL9458637 | 0.85 | ALOX5 (0.32) | ALOX5CYP19A1 | |
| SCHEMBL9380828 | 0.80 | ALOX5 (0.47) | ALOX5 | |
| SCHEMBL9381401 | 0.78 | ALOX5 (0.37) | ALOX5 | |
| SCHEMBL9440457 | 0.76 | ALOX5 (0.43) | ALOX5 | |
| SCHEMBL9458108 | 0.76 | ALOX5 (0.34) | ALOX5CYP19A1 | |
| SCHEMBL9384364 | 0.75 | — | — | |
| SCHEMBL9380123 | 0.74 | ALOX5 (0.39) | ALOX5 | |
| SCHEMBL9380308 | 0.72 | ALOX5 (0.41) | ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0409413-B1 | Diaryl ether heterocycles | ICI PLC (GB) | 1994-08-03 | — | — | EP | claimed |
| EP-0409413-A2 | Diaryl ether heterocycles | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-01-23 | — | — | EP | claimed |
| EP-0409413-B1 | Diaryl ether heterocycles | ICI PLC (GB) | 1994-08-03 | — | — | EP | disclosed |
| US-5208259-A | Lipoxygenase enzyme inhibitors | IMPERIAL CHEMICAL INDUSTRIES (GB) | 1993-05-04 | — | — | US | disclosed |
| EP-0409413-A2 | Diaryl ether heterocycles | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-01-23 | — | — | EP | disclosed |