Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 5/20 | 0.42 |
| ▸ | NOS1 | P29475 | 5/20 | 0.42 |
| ▸ | NOS2 | P35228 | 5/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | INMT | O95050 | 1/20 | 0.32 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.31 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7395015 | 0.97 | — | — | |
| Iodomethane SCHEMBL9434948 | 0.95 | NOS3 (0.39) | NOS3NOS1NOS2MEN1KMT2A | |
| Iodide SCHEMBL4248459 | 0.95 | — | — | |
| SCHEMBL1669865 | 0.90 | — | — | |
| SCHEMBL13545400 | 0.68 | LMNA (0.39) | NOS3NOS1NOS2MEN1KMT2A | |
| SCHEMBL24971583 | 0.65 | NOS3 (0.48) | NOS3NOS1NOS2MEN1KMT2A | |
| SCHEMBL14441515 | 0.65 | NOS3 (0.48) | NOS3NOS1NOS2MEN1KMT2A | |
| SCHEMBL16489783 | 0.65 | — | — | |
| SCHEMBL12422425 | 0.65 | NOS3 (0.48) | NOS3NOS1NOS2MEN1KMT2A | |
| SCHEMBL10296536 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0355645-B1 | Cyclic amidines and process for their preparation | BAYER AG (DE) | 1994-04-27 | — | — | EP | disclosed |
| EP-0355645-A2 | Cyclic amidines and process for their preparation | BAYER AG (DE) | 1990-02-28 | — | — | EP | disclosed |