SCHEMBL9380355

SCHEMBL9380355

CCNc1nc2ccc(C=Cc3nc(CC(c4ccccc4)(c4ccccc4)c4ccccc4)[nH]c3C)cc2o1

nearest known ligand 0.37

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ELANE P08246 3/20 0.37
GPR119 Q8TDV5 1/20 0.32
IP6K1 Q92551 1/20 0.31
UTRN P46939 1/20 0.30
MAPT P10636 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9380357 0.78 ELANE (0.34) ELANE
SCHEMBL10431679 0.77 ELANE (0.35) ELANEUTRNMAPT
SCHEMBL9376863 0.76 ELANE (0.35) ELANEUTRNMAPT
SCHEMBL9376854 0.76 ELANE (0.35) ELANEUTRNMAPT
SCHEMBL9380881 0.75 ELANE (0.36) ELANEIP6K1MAPT
SCHEMBL9380872 0.75 ELANE (0.36) ELANEIP6K1MAPT
SCHEMBL9380550 0.69 ELANE (0.40) ELANEMAPT
SCHEMBL9380547 0.69 ELANE (0.40) ELANEMAPT
SCHEMBL29045541 0.68 ELANE (0.44) ELANEMAPT
SCHEMBL9380627 0.66 ELANE (0.36) ELANEMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0356234-B1 New Benzazole compounds, processes for the preparation thereof and pharmaceutical composition comprising the same FUJISAWA PHARMACEUTICAL CO (JP) 1994-05-11 EP disclosed