Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 2/20 | 0.36 |
| ▸ | IP6K1 | Q92551 | 4/20 | 0.32 |
| ▸ | IP6K3 | Q96PC2 | 2/20 | 0.32 |
| ▸ | IP6K2 | Q9UHH9 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | ATP4A | P20648 | 2/20 | 0.31 |
| ▸ | ATP4B | P51164 | 2/20 | 0.31 |
| ▸ | QPCT | Q16769 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.30 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.30 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9380881 | 1.00 | ELANE (0.36) | ELANEIP6K1IP6K3IP6K2HDAC1 | |
| SCHEMBL9380355 | 0.75 | ELANE (0.37) | ELANEIP6K1MAPT | |
| SCHEMBL9380111 | 0.74 | HRH2 (0.37) | ELANEQPCTMAPTTDP1 | |
| SCHEMBL29045541 | 0.74 | ELANE (0.44) | ELANEALDH1A1MAPT | |
| SCHEMBL9380547 | 0.74 | ELANE (0.40) | ELANEALDH1A1LMNAMAPTTDP1 | |
| SCHEMBL9380550 | 0.74 | ELANE (0.40) | ELANEALDH1A1LMNAMAPTTDP1 | |
| SCHEMBL9376854 | 0.73 | ELANE (0.35) | ELANEMAPT | |
| SCHEMBL9376863 | 0.73 | ELANE (0.35) | ELANEMAPT | |
| SCHEMBL9380631 | 0.72 | ELANE (0.36) | ELANEHDAC1ALDH1A1MAPTOPRK1 | |
| SCHEMBL9380627 | 0.72 | ELANE (0.36) | ELANEHDAC1ALDH1A1MAPTOPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0356234-B1 | New Benzazole compounds, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO (JP) | 1994-05-11 | — | — | EP | disclosed |
| US-5047411-A | Antiulcer Agents, H2-Receptor Antagonists | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-09-10 | — | — | US | disclosed |
| EP-0356234-A2 | New Benzazole compounds, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1990-02-28 | — | — | EP | disclosed |