Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 3/20 | 0.41 |
| ▸ | NOS3 | P29474 | 2/20 | 0.41 |
| ▸ | NOS2 | P35228 | 2/20 | 0.41 |
| ▸ | GRM5 | P41594 | 1/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | KMO | O15229 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | THPO | P40225 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | OGT | O15294 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9385343 | 0.87 | NOS1 (0.38) | NOS1NOS3NOS2GRM5MCL1 | |
| SCHEMBL9382154 | 0.76 | GRIN2D (0.38) | NOS1NOS3NOS2GRM5KDM4E | |
| SCHEMBL11040536 | 0.74 | NOS1 (0.49) | NOS1NOS3NOS2GRM5MCL1 | |
| SCHEMBL520456 | 0.70 | NOS1 (0.41) | NOS1NOS3NOS2GRM5MCL1 | |
| SCHEMBL18188217 | 0.70 | KMO (0.35) | NOS1NOS3NOS2MCL1KMO | |
| SCHEMBL5541374 | 0.70 | NOS1 (0.49) | NOS1NOS3NOS2GRM5MCL1 | |
| SCHEMBL9384780 | 0.70 | NOS1 (0.49) | NOS1NOS3NOS2GRM5MCL1 | |
| SCHEMBL5544216 | 0.68 | MCL1 (0.47) | NOS1NOS3NOS2GRM5MCL1 | |
| SCHEMBL7067142 | 0.67 | KMO (0.52) | NOS1NOS3NOS2KMOKDM4E | |
| SCHEMBL522196 | 0.67 | NOS1 (0.53) | NOS1NOS3NOS2KMOKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0409484-B1 | 4,5,6,7-Tetrasubstituted benzoxazolones | PFIZER (US) | 1994-06-08 | — | — | EP | disclosed |
| US-5071863-A | Antiallergens; antiinflammatory agents; enzyme inhibitors | PFIZER INC. (US) | 1991-12-10 | — | — | US | disclosed |
| EP-0409484-A2 | 4,5,6,7-Tetrasubstituted benzoxazolones | PFIZER INC. (US) | 1991-01-23 | — | — | EP | disclosed |