Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | F2 | P00734 | 1/20 | 0.50 |
| ▸ | PLG | P00747 | 1/20 | 0.50 |
| ▸ | PLAU | P00749 | 1/20 | 0.50 |
| ▸ | PLAT | P00750 | 1/20 | 0.50 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.50 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.50 |
| ▸ | CYP26A1 | O43174 | 3/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | RARA | P10276 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | CYP26B1 | Q9NR63 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAPK14 | Q16539 | 4/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9376041 | 0.89 | KDM4E (0.55) | MAPTCYP26A1CYP3A4RARARAB9A | |
| SCHEMBL9381158 | 0.87 | MAPT (0.48) | MAPTNPC1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL9375850 | 0.87 | KDM4E (0.50) | CYP26A1CYP3A4RARARAB9ANPC1 | |
| SCHEMBL9375240 | 0.86 | KMT2A (0.52) | CYP26A1CYP3A4RARARAB9ANPC1 | |
| SCHEMBL9376571 | 0.86 | CYP26A1 (0.52) | MAPTCYP26A1CYP3A4RARANPC1 | |
| SCHEMBL9375391 | 0.86 | CYP26A1 (0.52) | MAPTCYP26A1CYP3A4RARARAB9A | |
| SCHEMBL9376140 | 0.86 | NPC1 (0.52) | MAPTCYP26A1CYP3A4RARARAB9A | |
| SCHEMBL9840186 | 0.85 | CYP26A1 (0.51) | MAPTCYP26A1CYP3A4RARARAB9A | |
| SCHEMBL9379538 | 0.85 | MEN1 (0.53) | CYP26A1CYP3A4RARARAB9ANPC1 | |
| SCHEMBL9375261 | 0.85 | BACE1 (0.55) | MAPTCYP26A1CYP3A4RARARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0344634-B1 | Bicyclic carboxamides, process for their preparation and medicaments containing them | BOEHRINGER MANNHEIM GMBH (DE) | 1994-03-30 | — | — | EP | disclosed |
| US-5019587-A | Anticoagulants | BOEHRINGER MANNHEIM GMBH (DE) | 1991-05-28 | — | — | US | disclosed |
| EP-0344634-A1 | Bicyclic carboxamides, process for their preparation and medicaments containing them | Roche Diagnostics GmbH (DE) | 1989-12-06 | — | — | EP | disclosed |