Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP26A1 | O43174 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.51 |
| ▸ | RARA | P10276 | 2/20 | 0.51 |
| ▸ | MAPK14 | Q16539 | 4/20 | 0.49 |
| ▸ | NPC1 | O15118 | 4/20 | 0.48 |
| ▸ | RAB9A | P51151 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.46 |
| ▸ | RELA | Q04206 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9375391 | 0.88 | CYP26A1 (0.52) | CYP26A1CYP3A4RARAMAPK14NPC1 | |
| SCHEMBL9376571 | 0.88 | CYP26A1 (0.52) | CYP26A1CYP3A4RARAMAPK14NPC1 | |
| SCHEMBL9380096 | 0.88 | LMNA (0.51) | CYP26A1CYP3A4RARAMAPK14NPC1 | |
| SCHEMBL9375261 | 0.87 | BACE1 (0.55) | CYP26A1CYP3A4RARAMAPK14NPC1 | |
| SCHEMBL9379538 | 0.87 | MEN1 (0.53) | CYP26A1CYP3A4RARAMAPK14NPC1 | |
| SCHEMBL9380901 | 0.87 | MEN1 (0.53) | CYP26A1CYP3A4RARAMAPK14NPC1 | |
| SCHEMBL9374793 | 0.87 | CYP26A1 (0.53) | CYP26A1CYP3A4RARAMAPK14KMT2A | |
| SCHEMBL9840194 | 0.86 | NPC1 (0.52) | MAPK14NPC1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL9375240 | 0.86 | KMT2A (0.52) | CYP26A1CYP3A4RARAMAPK14NPC1 | |
| SCHEMBL9380425 | 0.85 | MAPT (0.50) | CYP26A1CYP3A4RARAMAPK14NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991001986-A1 | N-(DIALKYLOXOPHOSPHINYLALKYL)-LACTAMS, PROCESS FOR PREPARING THEM AND DRUGS CONTAINING THEM | BOEHRINGER MANNHEIM GMBH (DE) | 1991-02-21 | — | — | WO | disclosed |