Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PI4KA | P42356 | 6/20 | 0.54 |
| ▸ | PI4KB | Q9UBF8 | 6/20 | 0.54 |
| ▸ | PIK3CD | O00329 | 6/20 | 0.54 |
| ▸ | PIK3CA | P42336 | 6/20 | 0.54 |
| ▸ | PIK3CG | P48736 | 5/20 | 0.54 |
| ▸ | RAB9A | P51151 | 4/20 | 0.54 |
| ▸ | NPC1 | O15118 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | SCN4A | P35499 | 1/20 | 0.54 |
| ▸ | PIP5K1C | O60331 | 3/20 | 0.51 |
| ▸ | SCD | O00767 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | SYK | P43405 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | AXL | P30530 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21177823 | 0.82 | RAB9A (0.60) | PI4KAPI4KBPIK3CDPIK3CAPIK3CG | |
| SCHEMBL8548185 | 0.78 | RAB9A (0.59) | PI4KAPI4KBPIK3CDPIK3CAPIK3CG | |
| SCHEMBL8122351 | 0.74 | RAB9A (0.76) | PI4KAPI4KBPIK3CDPIK3CAPIK3CG | |
| SCHEMBL17064838 | 0.72 | SLC6A2 (0.47) | PI4KAPI4KBMAPTCYP3A4ALDH1A1 | |
| SCHEMBL31067503 | 0.72 | SLC6A2 (0.47) | PI4KAPI4KBMAPTCYP3A4ALDH1A1 | |
| SCHEMBL5655372 | 0.72 | SLC6A3 (0.46) | PI4KAPI4KBSCDL3MBTL1MAPT | |
| SCHEMBL5655180 | 0.72 | SLC6A3 (0.46) | PI4KAPI4KBSCDL3MBTL1MAPT | |
| SCHEMBL5655181 | 0.72 | SLC6A3 (0.46) | PI4KAPI4KBSCDL3MBTL1MAPT | |
| SCHEMBL17064435 | 0.71 | SLC6A3 (0.39) | SCDL3MBTL1MAPTCYP3A4ALDH1A1 | |
| SCHEMBL31067445 | 0.71 | SLC6A3 (0.39) | SCDL3MBTL1MAPTCYP3A4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0356234-B1 | New Benzazole compounds, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO (JP) | 1994-05-11 | — | — | EP | disclosed |
| US-5047411-A | Antiulcer Agents, H2-Receptor Antagonists | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-09-10 | — | — | US | disclosed |
| EP-0356234-A2 | New Benzazole compounds, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1990-02-28 | — | — | EP | disclosed |