Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IP6K1 | Q92551 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | DHODH | Q02127 | 5/20 | 0.42 |
| ▸ | KLK7 | P49862 | 1/20 | 0.40 |
| ▸ | PRNP | P04156 | 1/20 | 0.39 |
| ▸ | MAT2A | P31153 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23946317 | 0.83 | KDM4E (0.53) | KDM4EALDH1A1MAPTLMNAHPGD | |
| SCHEMBL23946311 | 0.83 | KDM4E (0.53) | KDM4EALDH1A1MAPTLMNAHPGD | |
| SCHEMBL23946306 | 0.83 | KDM4E (0.53) | KDM4EALDH1A1MAPTLMNAHPGD | |
| SCHEMBL23946342 | 0.80 | KDM4E (0.50) | KDM4EALDH1A1MAPTLMNAHPGD | |
| SCHEMBL9380942 | 0.77 | IP6K1 (0.53) | IP6K1KDM4EALDH1A1MEN1NPC1 | |
| SCHEMBL13440485 | 0.77 | KDM4E (0.71) | KDM4EALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL29986553 | 0.76 | ADORA2A (0.57) | KDM4EALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL16542819 | 0.76 | ADORA2A (0.57) | KDM4EALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL23946246 | 0.76 | KDM4E (0.49) | KDM4EALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL23946244 | 0.75 | DHFR (0.50) | KDM4EALDH1A1MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0621276-A1 | Angiotensin II receptor blocking 2,3,6-substituted quinazolinones | AMERICAN CYANAMID COMPANY (US) | 1994-10-26 | — | — | EP | disclosed |